Meeting Examining the State of the Science of Mammalian Embryo Model Systems: A Workshop When: November 20, 2019 (8:30 AM Eastern) Where: National Academy of Sciences Building (Lecture Room) • 2101 Constitution Avenue, NW, Washington, DC 20418 Topic Biomedical and Health Research Activity: Examining the State of the Science of Mammalian Embryo Model Systems: A Workshop Board: Board on Health Sciences Policy An ad hoc committee will plan and conduct a one day public workshop to explore the state of the science of mammalian embryo model systems, including nonhuman primate and human models. The goal of the workshop will be to begin with an overview of the developments and uses that have set the foundation for the field, then to focus in on opportunities and challenges for future work with embryo model systems. Discussions may include topics such as the characteristics of advanced mammalian embryo model systems; differences between mammalian embryo model systems and bona fide mammalian embryos; and differences between mammalian embryo model systems and mammalian embryoid bodies (i.e. culture systems in which pluripotent stem cells aggregate and differentiate, but are not intended to fully replicate embryonic development). The functionality of synthetic model systems may be considered, including how they could be used to predict function in systems made with human cells.