Review of Adverse Effects of Vaccines

Type: Consensus Study
Topics: Diseases, Public Health, Quality and Patient Safety, Children and Families, Biomedical and Health Research
Board: Board on Population Health and Public Health Practice

Activity Description

The committee will review the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the Vaccine Injury Compensation Program. The vaccines to be reviewed are varicella zoster vaccine, influenza vaccines, hepatitis B vaccine, human papillomavirus vaccine, measles-mumps-rubella vaccine, hepatitis A vaccine, meningococcal vaccines, and tetanus-containing vaccines such as diphtheria and tetanus toxoids and-acellular pertussis vaccines. The committee will author a consensus report with conclusions on the evidence bearing on causality and the evidence regarding the biological mechanisms that underlie specific theories for how a specific vaccine is related to a specific adverse event. The project is sponsored by the U.S. Department of Health and Human Services. The approximate start date for the project is 25 September 2008. A report will be issued at the end of the project in September 2011.

Public Comment: If you have information you would like to share with the committee, you can do so by submitting your comment to the project e-mail at

Any comment you submit to the committee, including your name and identifying information will not be kept confidential and will be included in the Public Access File as the National Academy of Sciences complies with Section 15 of the Federal Advisory Committee Act (FACA). The National Academies shall be authorized to use any such comments or submissions in accordance with the National Academies’ Terms of Use Statement.

The project staff will use the vaccine safety mailing list to share information on activities of the Committee to Review Adverse Effects of Vaccines. The listserv will send one to three announcements per month about committee activities for the duration of the project.

To receive emails from our listserv, please click "Sign Up Now" under Stay Up To Date on this page. The listserv Review of Adverse Effects of Vaccines will be selected. 

Request for Input on Bibliography

The Committee to Review Adverse Effects of Vaccines has posted a bibliography of citations it has reviewed.  As a reminder, the committee is assessing epidemiological, clinical, and biological literature in order to make conclusions about the causal relationship between specific vaccines and specific adverse events. The bibliography can be found here.

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