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  • Immunization Safety Review: Health and Medicine Division
    The Immunization Safety Review Committee (ISR) is a project within the Institute of Medicine, that addresses current and emerging vaccine-safety concerns.
  • Adverse Effects of Vaccines: Evidence and Causality ...
    Immunizations are a cornerstone of the nation’s efforts to protect people from a host of infectious diseases. Though generally very rare or very minor, there are side effects, or “adverse effects,” associated with some vaccines. The IOM reviewed a list of adverse events associated with eight vaccines to evaluate the scientific evidence about the event–vaccine relationship. Using ...
  • Childhood Immunization Schedule and Safety: Stakeholder ...
    Vaccines are among the most safe and effective public health interventions to prevent serious disease and death. Health care providers who vaccinate young children follow a schedule prepared by the U.S. Advisory Committee on Immunization Practices. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some ...
  • The Anthrax Vaccine: Is It Safe? Does It Work?: Health ...
    The vaccine used to protect humans against the anthrax disease, called Anthrax Vaccine Adsorbed (AVA), was licensed in 1970. It was initially used primarily to protect people who might be exposed to anthrax where they worked, such as veterinarians and textile plant workers who process animal hair.
  • Immunization Safety Review: Vaccines and Autism: Health ...
    This eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which ...
  • Vaccine Safety Research, Data Access, and Public Trust ...
    The Vaccine Safety Datalink (VSD) is a large, linked database of patient information that was developed jointly by CDC and several private managed care organizations in 1991.
  • Few Health Problems Are Caused By Vaccines, IOM Report ...
    An analysis of more than 1,000 research articles concluded that few health problems are caused by or clearly associated with vaccines. A committee of experts convened by the Institute of Medicine to review the scientific literature on possible adverse effects of vaccines found convincing evidence of 14 health outcomes -- including seizures, inflammation of the brain, and fainting -- that can ...
  • Priorities for the National Vaccine Plan: Health and ...
    The National Vaccine Plan facilitates coordination of the vaccine enterprise across the United States. In this report, the IOM finds that although the National Vaccine Program has had some great successes and can provide examples of excellent coordination, the Plan has not functioned as intended.
  • SMART Vaccines: Update and Demonstration: Health and ...
    In this first phase report, the IOM offers a framework and proof of concept to account for various factors influencing vaccine prioritization—demographic, economic, health, scientific, business, programmatic, social, policy factors and public concerns.
  • Gulf War and Health: Volume 10: Update of Health Effects ...
    In response to the variety of health problems and symptoms reported by veterans, Congress passed two laws directing the Department of Veterans Affairs (VA) to contract with the Institute of Medicine (IOM) of the National Academies of Sciences, Engineering, and Medicine to review and evaluate the scientific and medical literature regarding associations between illness and exposure to toxic ...