About Publications

Publications from the National Academies of Sciences, Engineering, and Medicine provide objective and straightforward advice to decision makers and the public. This site includes Health and Medicine Division (HMD) publications released after 1998. A complete list of HMD’s publications from its establishment in 1970 to the present is available as a PDF.


  • Immunization Safety Review: Vaccines and Autism : Health ... Released: May 14, 2004
    This eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which these immunizations might cause autism. The committee concludes that the body of epidemiological evidence favors rejection of a causal relationship between the MMR vaccine and autism.
  • Immunization Safety Review: Influenza Vaccines and ... Released: October 06, 2003
    Infection with the influenza virus can have a serious effect on the health of people of all ages, although it is particularly worrisome for infants, the elderly, and people with underlying heart or lung problems. At least 35,000 people die in the United States every year from influenza infection. A vaccine exists (the influenza shot) that can greatly decrease the impact of influenza.
  • Financing Vaccines in the 21st Century: Assuring Access and ... Released: August 04, 2003
    Financing Vaccines in the 21st Century: Assuring Access and Availability addresses these challenges by proposing new strategies for assuring access to vaccines and sustaining the supply of current and future vaccines. The report proposes a federal mandate, subsidy and voucher program for vaccines.
  • Immunization Safety Review: Vaccinations and Sudden ... Released: March 31, 2003
    With current recommendations calling for infants to receive multiple doses of vaccines during their first year of life and with sudden infant death syndrome (SIDS) the most frequent cause of death during the postneonatal period, it is important to respond to concerns that vaccination might play a role in sudden unexpected infant death.
  • Immunization Safety Review: Multiple Immunizations and ... Released: February 20, 2002
    The Immunization Safety Review committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction, with a focus on evidence related to risk for infections, the autoimmune disease type I diabetes, and allergic disorders.
  • Immunization Safety Review: Measles-Mumps-Rubella ... Released: April 23, 2001
    The Centers for Disease Control and Prevention and the National Institutes of Health recognized the need for an independent group to carefully examine the hypothesized MMR-autism link and address other vaccine-safety issues as well, in order to give some guidance to themselves, health care providers, researchers, and a concerned public.
  • Calling the Shots: Immunization Finance Policies and ... Released: June 16, 2000
    At the request of the Senate Committee on Appropriations, the Institute of Medicine (IOM), an arm of the National Academy of Sciences, established a committee to examine the roles and responsibilities of state and federal gov-ernments in supporting immunization services and to identify basic strategies that could strengthen the national immunization system in the current health care climate.
  • Ending Neglect: The Elimination of Tuberculosis in the US ... Released: May 01, 2000
    Tuberculosis emerged as an epidemic in the 1600s, began to decline as sanitation improved in the 19th century, and retreated further when effective therapy was developed in the 1950s. TB was virtually forgotten until a recent resurgence in the U.S. and around the world-ominously, in forms resistant to commonly used medicines. In this report, Ending Neglect: The Elimination of Tuberculosis in the U.S., the committee offers recommendations in the key areas of epidemiology and prevention, diagnosis and treatment, funding and organization of public initiatives, and the U.S. role worldwide.
  • Vaccines for the 21st Century: A Tool for Decisionmaking ... Released: March 01, 1999
    This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades.