Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public–Private Partnerships: Proceedings of a Workshop


Note: Proceedings contain the opinion of the presenters, but do NOT reflect the conclusions of the Health and Medicine Division or the National Academies. Learn more about the differences between Reports and Proceedings.

Chronic pain is one of the most prevalent, costly, and disabling health conditions in the United States. In parallel with increasing recognition of the need to treat chronic pain, the opioid epidemic has emerged as a growing public health emergency. In 2017, the National Institutes of Health began exploring public-private partnerships to develop solutions to the opioid crisis and cut in half the time it takes to develop non-addictive analgesics. To help inform this effort, the National Academies’ Forum on Neuroscience and Nervous Systems Disorders hosted a public workshop that brought together experts and stakeholders from academia, federal agencies, advocacy organizations, and companies developing therapeutics for pain and opioid use disorders. Workshop discussions addressed public-private partnership approaches to improving understanding of the neurobiological mechanisms of pain, developing non-addictive pain treatments, and developing medications for opioid use disorders and for overdose prevention and reversal. The workshop rapporteurs have prepared this proceedings as a factual summation of the session discussions at the workshop.