Innovations in the diagnostic specialties have the potential to dramatically reshape cancer diagnosis and enable precision therapy. Spurred by advances in informatics, there are opportunities to combine and collate information from imaging, pathology, and molecular testing. Multidisciplinary collaboration among pathologists, radiologists, and oncologists—supplemented by machine-learning based tools—could facilitate a more precise understanding of a patient’s diagnosis and what treatment strategies may be most effective for improved patient outcomes. Integrated diagnostics also have the potential to improve patient access to subspecialty expertise, particularly in community-based settings of cancer care.
This National Academies workshop, convened by the National Cancer Policy Forum, in collaboration with the Academies’ Computer Science and Telecommunications Board, and the Board on Human-Systems Integration, was an opportunity for the cancer community to better define the purpose, goals, and components of integrated diagnostics. Workshop presentations and discussions examined the current state of integrated diagnostics in facilitating precision cancer care and highlight speaker perspectives on the vision for the future.
Planning Committee
Kojo S.J. Elenitoba-Johnson, Memorial Sloan Kettering Cancer Center (Co-chair)
Hedvig Hricak, Memorial Sloan Kettering Cancer Center (Co-chair)
Christina Chapman, Baylor College of Medicine
Nancy E. Davidson, Fred Hutchinson Cancer Center/University of Washington
Roy A. Jensen, The University of Kansas Cancer Center
Beth Y. Karlan, Jonsson Comprehensive Cancer Center, University of California, Los Angeles
Mia Levy, Foundation Medicine, Inc/Rush University
Aanand D. Naik, UTHealth
Wendy Nilsen, National Science Foundation
Jason M. Slagle, Vanderbilt University Medical Center
Speakers and Moderators
Gil Alterovitz, VA Health System
Regina Barzilay, Massachusetts Institute of Technology
Otis Brawley, Johns Hopkins University (participating virtually)
Atul Butte, University of California, San Francisco
Avishek Choudury, West Virginia University
Dorin Comaniciu, Siemens Healthineers
Nancy E. Davidson, Fred Hutchinson Cancer Center/University of Washington (participating virtually)
David Dorr, Oregon State Health and Science University
Kojo S.J. Elenitoba-Johnson, Memorial Sloan Kettering Cancer Center
Garry Gold, Stanford University School of Medicine
Lyndsay Harris, Cancer Diagnosis Program, NCI (participating virtually)
Bradford Hirsch, SignalPath, a Verily Company
Hedvig Hricak, Memorial Sloan Kettering Cancer Center
Roy A. Jensen, The University of Kansas Cancer Center
Beth Y. Karlan, Jonsson Comprehensive Cancer Center, University of California, Los Angeles
Gabriel Krestin, Erasmus MC (participating virtually)
Torbjörn Kronander, Sectra AB
Michael Laposata, University of Texas Medical Branch
Jochen K. Lennerz, Massachusetts General Hospital
Mia Levy, Foundation Medicine, Inc./Rush University
Jennifer Malin, Optum Health Solutions
Neal J. Meropol, Flatiron Health
Susan Monarez, ARPA-H (participating virtually)
Aanand D. Naik, UTHealth
Wendy Nilsen, National Science Foundation
Travis J. Osterman, Vanderbilt University Medical Center
Randall Oyer, Association of Community Cancer Centers and Penn Medicine Lancaster General Health
Reena Philip, Oncology Center of Excellence, Food and Drug Administration
Mary Politi, Washington University School of Medicine
CJ Robison, Oracle Health
Manuel Salto-Tellez, The Royal Marsden Hospital
Charles Sawyers, Memorial Sloan Kettering Cancer Center
Mitchell Schnall, University of Pennsylvania
Sohrab Shah, Memorial Sloan Kettering Cancer Center
Jason M. Slagle, Vanderbilt University Medical Center
My T. Thai, University of Florida
Nick Trentadue, Epic