The Roundtable on Public Interfaces of the Life Sciences monitored and sought to understand the intersections between different life science research communities and public audiences for topics that may spark public concerns, generate policy debates, or influence market dynamics. The vision of the Roundtable was for life scientists to understand the dynamics of public interfaces, and have access to the knowledge and tools needed to develop proactive, collaborative, science-based approaches to public interfaces about current and emerging topics in the life sciences.