The 2024 United States – European Union Transportation Research Symposium is entitled Global Pathways to Net-Zero: Social, Behavioral, and Technological Research and Innovation Strategies for Transportation Decarbonization. The symposium’s discussions will focus on four key challenges: accelerating the transition to electrification and other low- and zero-carbon fuels; ensuring a fair and just transition to net zero; creating a land use-transportation nexus that is sustainable and resilient; and enlisting and leveraging digitalization, AI, and other integrated system-of-systems technologies.