The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use (2020)

Chapter: Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients

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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Appendix G

Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients

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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
1 Dehydroepiandrosterone Pregnenolone Capsule Dehydroepiandrosterone Sodium Sulfate Anhydrous; Pregnenolone 15 mg; 75 mg
2 Dehydroepiandrosterone Pregnenolone Suspension Dehydroepiandrosterone Sodium Sulfate Anhydrous; Pregnenolone 16 mg/1 mL; 40 mg/1 mL
3 Dehydroepiandrosterone Testosterone Cream Testosterone; Dehydroepiandrosterone 20 mg/1 mL; 200 mg/1 mL
4 Dehydroepiandrosterone Testosterone Gel Dehydroepiandrosterone; Testosterone 15 mg/1 mL; 4 mg/1 mL
5 Dehydroepiandrosterone Testosterone Lozenge Testosterone; Dehydroepiandrosterone 2 mg; 15 mg
6 Estradiol Progesterone Capsule Estradiol; Progesterone 0.25 mg; 100 mg
7 Estradiol Progesterone Cream Estradiol; Progesterone 0.4 mg/1 mL; 40 mg/1 mL
8 Estradiol Progesterone Cream Estradiol; Progesterone 0.65 mg/1 mL; 125 mg/1 mL
9 Estradiol Progesterone Cream Estradiol; Progesterone 1.2 mg/1 mL; 150 mg/1 mL
10 Estradiol Progesterone Cream Estradiol; Progesterone 4.2 mg/1 mL; 200 mg/1 mL
11 Estradiol Estriol Capsule Estradiol; Estriol 0.09 mg; 0.36 mg
12 Estradiol Estriol Capsule Estradiol; Estriol 0.25 mg; 0.25 mg
13 Estradiol Estriol Capsule Estradiol; Estriol 0.25 mg; 1 mg
14 Estradiol Estriol Capsule Estradiol; Estriol 0.3 mg; 0.3 mg
15 Estradiol Estriol Capsule Estradiol; Estriol 0.5 mg; 0.5 mg
16 Estradiol Estriol Capsule Estradiol; Estriol 0.625 mg; 0.625 mg
17 Estradiol Estriol Capsule Estradiol; Estriol 0.75 mg; 3 mg
18 Estradiol Estriol Capsule Estriol; Estradiol 1.25 mg
Page 291 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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19 Estradiol Estriol Capsule Bi-Estrogen Oral Capsule: (Estriol/Estradiol) 60/40 or 70/30 or 80/20 1.25 mg; 2.5 mg
20 Estradiol Estriol Capsule Estradiol; Estriol 1.5 mg; 1.5 mg
21 Estradiol Estriol Capsule Estriol; Estradiol 2.5 mg
22 Estradiol Estriol Capsule Estriol; Estradiol 5 mg
23 Estradiol Estriol Cream Bi-Est 50:50 (50% Estradiol, 50% Estriol) Cream 0.25 mg; 0.5 mg; 0.75 mg; 1 mg
24 Estradiol Estriol Cream Estradiol; Estriol 0.1 mg/0.5 g; 0.1 mg/0.5 g
25 Estradiol Estriol Cream Estradiol; Estriol 0.1 mg/0.5 g; 0.1 mg/0.5 g
26 Estradiol Estriol Cream Estradiol; Estriol 0.1 mg/0.5 g; 0.1 mg/0.5 g
27 Estradiol Estriol Cream Estradiol; Estriol 0.1 mg/1 mL; 0.4 mg/1 mL
28 Estradiol Estriol Cream Estradiol; Estriol 0.125 mg/1 mL; 0.5 mg/1 mL
29 Estradiol Estriol Cream Estradiol; Estriol 0.15 mg/0.5 g; 0.15 mg/0.5 g
30 Estradiol Estriol Cream Estradiol; Estriol 0.2 mg/1 mL; 0.8 mg/1 mL
31 Estradiol Estriol Cream Estradiol; Estriol 0.25 mg/1 mL; 0.25 mg/1 mL
32 Estradiol Estriol Cream Estradiol; Estriol 0.25 mg/1 mL; 1 mg/1 mL
33 Estradiol Estriol Cream Estradiol; Estriol 0.375 mg/1 mL; 0.375 mg/1 mL
34 Estradiol Estriol Cream Estradiol; Estriol 0.4 mg/1 g; 0.4 mg/1 g
35 Estradiol Estriol Cream Estradiol; Estriol 0.4 mg/1 mL; 0.4 mg/1 mL
36 Estradiol Estriol Cream Estradiol; Estriol 0.4 mg/1 mL; 1.6 mg/1 mL
37 Estradiol Estriol Cream Estradiol; Estriol 0.5 mg/1 g; 2 mg/1 g
38 Estradiol Estriol Cream Estradiol; Estriol 0.5 mg/1 g; 2 mg/1 g
Page 292 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
39 Estradiol Estriol Cream Estradiol; Estriol 0.5 mg/1 g; 2.5 mg/1 g
40 Estradiol Estriol Cream Estradiol; Estriol 0.5 mg/1 mL; 0.5 mg/1 mL
41 Estradiol Estriol Cream Estradiol; Estriol 0.5 mg/1 mL; 2 mg/1 mL
42 Estradiol Estriol Cream Estradiol; Estriol 0.6 mg/1 mL; 0.6 mg/1 mL
43 Estradiol Estriol Cream Estradiol; Estriol 0.8 mg/1 mL; 0.8 mg/1 mL
44 Estradiol Estriol Cream Estradiol; Estriol 0.8 mg/1 mL; 3.2 mg/1 mL
45 Estradiol Estriol Cream Estradiol; Estriol 1 mg/1 mL; 1 mg/1 mL
46 Estradiol Estriol Cream Estradiol; Estriol 1 mg/1 mL; 4 mg/1 mL
47 Estradiol Estriol Cream Estradiol; Estriol 1.2 mg/1 mL; 1.2 mg/1 mL
48 Estradiol Estriol Cream Estradiol; Estriol 1.25 mg/1 mL; 1.25 mg/1 mL
49 Estradiol Estriol Cream Bi-Estrogen Cream: (Estriol/Estradiol) 50/50 or 60/40 or 70/30 or 80/20 1.25 mg/0.1 mL; 2.5 mg/0.1 mL
50 Estradiol Estriol Cream Estradiol; Estriol 1.5 mg/1 mL; 3.5 mg/1 mL
51 Estradiol Estriol Cream Estradiol; Estriol 2 mg/1 g; 3 mg/1 g
52 Estradiol Estriol Cream Estradiol; Estriol 2 mg/1 mL; 2 mg/1 mL
53 Estradiol Estriol Cream Estriol; Estradiol 2 mg/g; 0.5 mg/g
54 Estradiol Estriol Cream Estradiol; Estriol 2.5 mg/1 mL; 2.5 mg/1 mL
55 Estradiol Estriol Cream Estradiol; Estriol 3 mg/1 mL; 2 mg/1 mL
56 Estradiol Estriol Cream Estradiol; Estriol 5 mg/1 mL; 5 mg/1 mL
57 Estradiol Estriol Cream Estradiol; Estriol 6.25 mg/1 mL; 6.25 mg/1 mL
58 Estradiol Estriol Gel Estradiol; Estriol 1.25 mg/1 mL; 1.25 mg/1 mL
Page 293 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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59 Estradiol Estriol Gel Estriol; Estradiol 2 mg/mL; 0.5 mg/mL
60 Estradiol Estriol Lozenge Estriol; Estradiol 0.3125 mg; 0.9375 mg
61 Estradiol Estriol Lozenge Estriol; Estradiol 0.5 mg; 0.125 mg
62 Estradiol Estriol Lozenge Estriol; Estradiol 0.6 mg; 0.15 mg
63 Estradiol Estriol Ointment Estradiol; Estriol 0.5 mg/1 g; 2 mg/1 g
64 Estradiol Estriol Ointment Estradiol; Estriol 0.5 mg/1 g; 2 mg/1 g
65 Estradiol Estriol Ointment Estradiol; Estriol 1 mg/1 g; 1.5 mg/1 g
66 Estradiol Estriol Solution Estradiol; Estriol 1.25 mg/1 mL; 1.25 mg/1 mL
67 Estradiol Estriol Solution Estradiol; Estriol 2 mg/1 mL; 8 mg/1 mL
68 Estradiol Estriol Solution Estriol; Estradiol 2 mg; 0.25 mg/mL
69 Estradiol Testosterone Cream Estradiol; Testosterone 0.3 mg/1 mL; 1 mg/1 mL
70 Estradiol Testosterone Cream Estradiol; Testosterone 0.3 mg/1 mL; 1 mg/1 mL
71 Estradiol Testosterone Cream Estradiol; Testosterone 0.4 mg/1 mL; 2 mg/1 mL
72 Estradiol Testosterone Cream Estradiol; Testosterone 0.5 mg/1 mL; 0.75 mg/1 mL
73 Estradiol Testosterone Ointment Estradiol; Testosterone 0.3 mg/1 g; 0.1 mg/1 g
74 Estradiol Testosterone Ointment Estradiol; Testosterone 0.3 mg/1 g; 1 mg/1 g
75 Estradiol Testosterone Ointment Estradiol; Testosterone 1 mg/1 g; 0.5 mg/1 g
76 Estriol Progesterone Cream Progesterone; Estriol 25 mg/1 g; 3 mg/1 g
77 Estriol Testosterone Cream Testosterone; Estriol 0.5 mg/1 g; 2 mg/1 g
78 Estriol Testosterone Cream Estriol; Testosterone 1 mg/1 g; 3 mg/1 g
79 Estriol Testosterone Cream Estriol; Testosterone 1 mg/1 g; 3 mg/1 g
80 Estriol Testosterone Cream Estriol; Testosterone; Desonide 10 mg/1 g; 2.5 mg/1 g; 0.5 mg/1 g
81 Estriol Testosterone Cream Testosterone; Estriol 4 mg/1 g; 6 mg/1 g
Page 294 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
82 Estriol Testosterone Gel Testosterone; Estriol 0.25 mg/1 g; 0.5 mg/1 g
83 Estriol Testosterone Gel Estriol; Testosterone 0.25 mg/1 mL; 2 mg/1 mL
84 Estriol Testosterone Ointment Lidocaine Hydrochloride; Testosterone; Estriol 50 mg/1 g; 0.5 mg/1 g; 2.5 mg/1 g
85 Estriol Testosterone Suppository Estriol; Testosterone 2 mg; 0.5 mg
86 Pregnenolone Progesterone Cream Progesterone; Pregnenolone 150 mg/1 mL; 5 mg/1 mL
87 Progesterone Testosterone Capsule Progesterone; Methyltestosterone 100 mg; 1.25 mg
88 Progesterone Testosterone Cream Testosterone; Progesterone 2 mg/1 g; 100 mg/1 g
89 Progesterone Testosterone Cream Testosterone; Progesterone 2 mg/1 g; 200 mg/1 g
90 Progesterone Testosterone Cream Testosterone; Progesterone 2 mg/1 g; 50 mg/1 g
91 Progesterone Testosterone Cream Progesterone; Testosterone 20 mg/0.5 g; 1.25 mg/0.5 g
92 Progesterone Testosterone Cream Progesterone; Testosterone 225 mg/1 mL; 0.5 mg/1 mL
93 Progesterone Testosterone Cream Progesterone; Testosterone 30 mg/1 mL; 0.25 mg/1 mL
94 Progesterone Testosterone Cream Progesterone; Testosterone 30 mg/1 mL; 2 mg/1 mL
95 Progesterone Testosterone Cream Testosterone; Progesterone 4 mg/1 g; 200 mg/1 g
96 Progesterone Testosterone Cream Testosterone; Progesterone 4 mg/1 g; 50 mg/1 g
97 Progesterone Testosterone Cream Testosterone; Progesterone 4 mg/1 g; 70 mg/1 g
98 Testosterone Cypionate; Testosterone Propionate Injection Testosterone Cypionate; Testosterone Propionate 160 mg/200 mg; 40 mg/200 mg
99 Testosterone Cypionate; Testosterone Propionate Injection Testosterone Propionate; Testosterone Cypionate 20 mg/1 mL; 200 mg/1 mL
100 Testosterone Cypionate; Testosterone Propionate Injection Testosterone Propionate; Testosterone Cypionate 20 mg/1 mL; 200 mg/1 mL
Page 295 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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101 Dehydroepiandrosterone; Estradiol; Estriol Cream Estriol; Estradiol; 7-Keto-Dehydroepiandrosterone 1.25 mg/1 mL; 1.25 mg/1 mL; 20 mg/1 mL
102 Dehydroepiandrosterone; Estriol; Progesterone Lozenge Estriol; Progesterone; 7-Keto-Dehydroepiandrosterone 1 mg; 10 mg; 10 mg
103 Dehydroepiandrosterone; Estriol; Progesterone Lozenge Estriol; Progesterone; 7-Keto-Dehydroepiandrosterone 1 mg; 15 mg; 10 mg
104 Dehydroepiandrosterone; Pregnenolone; Progesterone Capsule Progesterone; Dehydroepiandrosterone Sodium Sulfate Anhydrous; Pregnenolone 100 mg; 10 mg; 10 mg
105 Dehydroepiandrosterone; Pregnenolone; Progesterone Cream Progesterone; Pregnenolone; Dehydroepiandrosterone 125 mg/1 mL; 10 mg/1 mL; 10 mg/1 mL
106 Dehydroepiandrosterone; Pregnenolone; Progesterone Cream Dehydroepiandrosterone; Progesterone; Pregnenolone 5 mg/1 mL; 100 mg/1 mL; 10 mg/1 mL
107 Dehydroepiandrosterone; Progesterone; Testosterone Cream 7-Keto-Dehydroepiandrosterone; Testosterone; Progesterone 2 mg/1 g; 1 mg/1 g; 160 mg/1 g
108 Estradiol; Progesterone; Testosterone Capsule Progesterone; Estradiol, Testosterone
109 Estradiol; Progesterone; Testosterone Capsule Estradiol; Methyltestosterone; Progesterone 0.85 mg; 1.5 mg; 175 mg
110 Estradiol; Progesterone; Testosterone Capsule Estradiol; Progesterone; Methyltestosterone 1.1 mg; 165 mg; 1 mg
111 Estradiol; Progesterone; Testosterone Capsule Estradiol; Methyltestosterone; Progesterone 1.3 mg; 2.75 mg; 160 mg
112 Estradiol; Progesterone; Testosterone Capsule Estradiol; Methyltestosterone; Progesterone 1.9 mg; 1 mg; 170 mg
113 Estradiol; Progesterone; Testosterone Cream Estradiol; Testosterone; Progesterone 0.4 mg/1 mL; 2.2 mg/1 mL; 85 mg/1 mL
Page 296 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
114 Estradiol; Progesterone; Testosterone Cream Estradiol; Testosterone; Progesterone 0.55 mg/1 mL; 1.5 mg/1 mL; 95 mg/1 mL
115 Estradiol; Progesterone; Testosterone Cream Estradiol; Testosterone; Progesterone 0.65 mg/1 mL; 1.5 mg/1 mL; 125 mg/1 mL
116 Estradiol; Progesterone; Testosterone Cream Estradiol; Testosterone; Progesterone 0.7 mg/1 mL; 1.5 mg/1 mL; 135 mg/1 mL
117 Estradiol; Progesterone; Testosterone Cream Estradiol; Testosterone; Progesterone 2 mg/1 mL; 0.5 mg/1 mL; 125 mg/1 mL
118 Estradiol Estriol; Estrone Capsule Estradiol; Estriol; Estrone 0.25 mg; 2 mg; 0.25 mg
119 Estradiol Estriol; Estrone Capsule Estradiol; Estriol; Estrone 2.5 mg
120 Estradiol Estriol; Estrone Capsule Estradiol; Estriol; Estrone 2.5 mg
121 Estradiol Estriol; Estrone Capsule Estradiol; Estriol; Estrone 2.5 mg
122 Estradiol Estriol; Estrone Capsule Estradiol; Estriol; Estrone 2.5 mg
123 Estradiol Estriol; Estrone Capsule Estradiol; Estriol; Estrone 2.5 mg
124 Estradiol Estriol; Estrone Cream Estradiol; Estriol; Estrone 0.25 mg/g; 2 mg/g; 0.25 mg/g
125 Estradiol Estriol; Estrone Cream Estriol; Estradiol; Estrone 10 mg/1 mL; 1.25 mg/1 mL; 1.25 mg/1 mL
126 Estradiol Estriol; Estrone Gel Estradiol; Estriol; Estrone 2.5 mg/0.1 mL
127 Estradiol Estriol; Estrone Injection Estradiol; Estriol; Estrone 2.5 mg/mL
128 Estradiol Estriol; Estrone Solution Estradiol; Estriol; Estrone 0.25 mg/mL; 2 mg/mL; 0.25 mg/mL
129 Estradiol Estriol; Estrone Solution Estradiol; Estriol; Estrone 2.5 mg/0.1 mL
130 Estradiol Estriol; Estrone Tablet Estradiol; Estriol; Estrone 2.5 mg
131 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.05 mg; 125 mg; 0.45 mg
Page 297 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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132 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.06 mg; 100 mg; 0.24 mg
133 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.06 mg; 125 mg; 0.24 mg
134 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.08 mg; 100 mg; 0.32 mg
135 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.1 mg; 100 mg; 0.1 mg
136 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.1 mg; 70 mg; 0.4 mg
137 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.12 mg; 50 mg; 0.28 mg
138 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.15 mg; 80 mg; 0.15 mg
139 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.16 mg; 50 mg; 0.64 mg
140 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.25 mg; 50 mg; 1 mg
141 Estradiol Estriol; Progesterone Capsule Estriol; Estradiol; Progesterone 0.32 mg; 0.08 mg; 125 mg
142 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.5 mg; 120 mg; 0.5 mg
143 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 0.5 mg; 125 mg; 0.5 mg
144 Estradiol Estriol; Progesterone Capsule Estradiol; Progesterone; Estriol 1.15 mg; 175 mg; 1.15 mg
145 Estradiol Estriol; Progesterone Cream Estradiol; Progesterone; Estriol 0.08 mg/1 mL; 10 mg/1 mL; 0.32 mg/1 mL
Page 298 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
146 Estradiol Estriol; Progesterone Cream Estradiol; Progesterone; Estriol 0.08 mg/1 mL; 30 mg/1 mL; 0.32 mg/1 mL
147 Estradiol Estriol; Progesterone Cream Estriol; Estradiol; Progesterone 0.1 mg/1 mL; 0.1 mg/1 mL; 40 mg/1 mL
148 Estradiol Estriol; Progesterone Cream Estriol; Estradiol; Progesterone 0.25 mg/1 mL; 0.25 mg/1 mL; 25 mg/1 mL
149 Estradiol Estriol; Progesterone Cream Estradiol; Progesterone; Estriol 0.25 mg/1 mL; 200 mg/1 mL; 0.25 mg/1 mL
150 Estradiol Estriol; Progesterone Cream Estradiol; Progesterone; Estriol 0.25 mg/1 mL; 25 mg/1 mL; 0.25 mg/1 mL
151 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 0.5 mg/1 g; 200 mg/1 g; 0.5 mg/1 g
152 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 0.5 mg/1 g; 200 mg/1 g; 0.5 mg/1 g
153 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 0.5 mg/1 g; 40 mg/1 g; 0.5 mg/1 g
154 Estradiol Estriol; Progesterone Cream Estradiol; Progesterone; Estriol 0.5 mg/1 mL; 30 mg/1 mL; 0.5 mg/1 mL
155 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 0.8 mg/1 g; 20 mg/1 g; 0.2 mg/1 g
156 Estradiol Estriol; Progesterone Cream Estriol, Estradiol; Progesterone 0.2%; 0.2%; 12.5%
157 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 1 mg/1 g; 100 mg/1 g; 1 mg/1 g
158 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 1 mg/1 g; 100 mg/1 g; 1 mg/1 g
Page 299 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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159 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 1 mg/1 g; 100 mg/1 g; 1 mg/1 g
160 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 1 mg/1 g; 200 mg/1 g; 1 mg/1 g
161 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 1 mg/1 g; 40 mg/1 g; 0.25 mg/1 g
162 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 1 mg/1 g; 50 mg/1 g; 1 mg/1 g
163 Estradiol Estriol; Progesterone Cream Estriol; Estradiol; Progesterone 1 mg/1 mL; 0.25 mg/1 mL; 100 mg/1 mL
164 Estradiol Estriol; Progesterone Cream Estriol; Progesterone; Estradiol 2 mg/1 g; 160 mg/1 g; 2 mg/1 g
165 Estradiol Estriol; Progesterone Cream Estradiol; Progesterone; Estriol 2.5 mg/1 mL; 50 mg/1 mL; 2.5 mg/1 mL
166 Estradiol Estriol; Progesterone Cream Progesterone; Estriol; Estradiol 20 mg/0.5 g; 0.1 mg/0.5 g; 0.1 mg/0.5 g
167 Estradiol Estriol; Progesterone Cream Progesterone; Estriol; Estradiol 20 mg/1 mL; 0.2 mg/1 mL; 0.05 mg/1 mL
168 Estradiol Estriol; Progesterone Lozenge Estradiol; Progesterone; Estriol 0.16 mg; 200 mg; 0.64 mg
169 Estradiol Estriol; Progesterone Lozenge Estradiol; Progesterone; Estriol 2.8 mg; 120 mg; 11.2 mg
170 Estradiol Estriol; Progesterone Lozenge Progesterone; Estriol; Estradiol 25 mg; 2.4 mg; 0.6 mg
171 Estradiol Estriol; Progesterone Lozenge Progesterone; Estriol; Estradiol 30 mg; 1.6 mg; 0.4 mg
172 Estradiol Estriol; Progesterone Lozenge Progesterone; Estriol; Estradiol 30 mg; 2 mg; 0.5 mg
Page 300 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
173 Estradiol Estriol; Testosterone Cream Estriol; Estradiol; Testosterone 0.2 mg/0.5 g; 0.2 mg/0.5 g; 1 mg/0.5 g
174 Estradiol Estriol; Testosterone Cream Estriol; Estradiol; Testosterone 0.25 mg/1 mL; 0.25 mg/1 mL; 2 mg/1 mL
175 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 0.25 mg/1 mL; 0.5 mg/1 mL; 1 mg/1 mL
176 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 0.3 mg/1 mL; 1 mg/1 mL; 1.2 mg/1 mL
177 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 0.5 mg/1 mL; 0.5 mg/1 mL; 0.5 mg/1 mL
178 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 0.5 mg/1 mL; 1 mg/1 mL; 0.5 mg/1 mL
179 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 0.5 mg/1 mL; 1.5 mg/1 mL; 0.5 mg/1 mL
180 Estradiol Estriol; Testosterone Cream Estriol; Estradiol; Testosterone 1 mg/1 g; 1 mg/1 g; 2 mg/1 g
181 Estradiol Estriol; Testosterone Cream Estriol; Estradiol; Testosterone 1 mg/1 g; 1 mg/1 g; 4 mg/1 g
182 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 1 mg/1 mL; 1 mg/1 mL; 1 mg/1 mL
183 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 1 mg/1 mL; 3 mg/1 mL; 1 mg/1 mL
184 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 2 mg/1 mL; 1 mg/1 mL; 8 mg/1 mL
185 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 2 mg/1 mL; 1.5 mg/1 mL; 2 mg/1 mL
Page 301 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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186 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 3 mg/1 mL; 4 mg/1 mL; 3 mg/1 mL
187 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 3.75 mg/1 mL; 2.5 mg/1 mL; 3.75 mg/1 mL
188 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 4 mg/1 mL; 6 mg/1 mL; 4 mg/1 mL
189 Estradiol Estriol; Testosterone Cream Estradiol; Testosterone; Estriol 5 mg/1 mL; 2.5 mg/1 mL; 5 mg/1 mL
190 Estriol; Progesterone; Testosterone Cream Testosterone; Estriol; Progesterone 4 mg/1 g; 6 mg/1 g; 100 mg/1 g
191 Dehydroepiandrosterone; Estradiol; Progesterone; Testosterone Capsule Estradiol; Methyltestosterone; Progesterone; Dehydroepiandrosterone 0.75 mg; 1.5 mg; 150 mg; 7.5 mg
192 Dehydroepiandrosterone; Estradiol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Dehydroepiandrosterone 0.35 mg/1 mL; 150 mg/1 mL; 1.9 mg/1 mL; 7 mg/1 mL
193 Dehydroepiandrosterone; Estradiol; Estriol; Progesterone Capsule Estradiol; Progesterone; Dehydroepiandrosterone; Estriol 0.85 mg; 95 mg; 5 mg; 0.35 mg
194 Dehydroepiandrosterone; Estradiol; Estriol; Progesterone Cream Estriol; Estradiol; Progesterone; 7-Keto-Dehydroepiandrosterone 0.05 mg/1 mL; 0.05 mg/1 mL; 15 mg/1 mL; 6 mg/1 mL
195 Dehydroepiandrosterone; Estradiol; Estriol; Progesterone Cream Estradiol; Progesterone; Dehydroepiandrosterone; Estriol 0.12 mg/1 mL; 40 mg/1 mL; 2 mg/1 mL; 0.48 mg/1 mL
196 Dehydroepiandrosterone; Estradiol; Estriol; Progesterone Cream Estriol; Estradiol; 7-Keto-Dehydroepiandrosterone; Progesterone 0.7 mg/1 mL; 0.3 mg/1 mL; 5 mg/1 mL; 40 mg/1 mL
Page 302 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
197 Dehydroepiandrosterone; Estradiol; Estriol; Testosterone Cream Estradiol; Testosterone; Estriol; Dehydroepiandrosterone 0.225 mg/1 mL; 1.5 mg/1 mL; 0.225 mg/1 mL; 5 mg/1 mL
198 Dehydroepiandrosterone; Estradiol; Estriol; Testosterone Cream Estradiol; Testosterone; Estriol; Dehydroepiandrosterone 0.225 mg/1 mL; 3 mg/1 mL; 0.225 mg/1 mL; 5 mg/1 mL
199 Dehydroepiandrosterone; Estradiol; Estriol; Testosterone Cream Estriol; Estradiol; Testosterone; 7-Keto-Dehydroepiandrosterone 1.25 mg/1 mL; 1.25 mg/1 mL; 4 mg/1 mL; 20 mg/1 mL
200 Estradiol; Estriol; Estrone; Progesterone Capsule Estradiol; Progesterone; Estriol; Estrone 0.125 mg; 50 mg; 1 mg; 0.125 mg
201 Estradiol; Estriol; Progesterone; Testosterone Capsule Estradiol; Progesterone; Testosterone; Estriol 0.1 mg; 150 mg; 2 mg; 0.4 mg
202 Estradiol; Estriol; Progesterone; Testosterone Capsule Estriol; Estradiol; Progesterone; Testosterone 2.5 mg; 50 mg; 1 mg
203 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.02 mg/1 mL; 125 mg/1 mL; 2 mg/1 mL; 0.08 mg/1 mL
204 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.08 mg/1 mL; 20 mg/1 mL; 1 mg/1 mL; 0.32 mg/1 mL
205 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.15 mg/1 mL; 100 mg/1 mL; 4 mg/1 mL; 0.35 mg/1 mL
206 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.2 mg/1 mL; 150 mg/1 mL; 0.5 mg/1 mL; 0.8 mg/1 mL
207 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.2 mg/1 mL; 30 mg/1 mL; 0.5 mg/1 mL; 0.3 mg/1 mL
208 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.25 mg/1 mL; 30 mg/1 mL; 1 mg/1 mL; 0.25 mg/1 mL
Page 303 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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209 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.3 mg/1 mL; 25 mg/1 mL; 0.25 mg/1 mL; 1 mg/1 mL
210 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.3 mg/1 mL; 40 mg/1 mL; 1 mg/1 mL; 0.3 mg/1 mL
211 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.4 mg/1 mL; 200 mg/1 mL; 0.5 mg/1 mL; 1.6 mg/1 mL
212 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.4 mg/1 mL; 200 mg/1 mL; 2 mg/1 mL; 1.6 mg/1 mL
213 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 100 mg/1 g; 1 mg/1 g
214 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 100 mg/1 g; 2 mg/1 g
215 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 100 mg/1 g; 2 mg/1 g
216 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 150 mg/1 g; 2 mg/1 g
217 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 200 mg/1 g; 2 mg/1 g
218 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 200 mg/1 g; 2 mg/1 g
219 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 50 mg/1 g; 2 mg/1 g
220 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.5 mg/1 g; 0.5 mg/1 g; 80 mg/1 g; 3 mg/1 g
221 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Testosterone; Progesterone 0.5 mg/1 mL; 0.5 mg/1 mL; 0.5 mg/1 mL; 60 mg/1 mL
222 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Testosterone; Progesterone 0.5 mg/1 mL; 0.5 mg/1 mL; 0.5 mg/1 mL; 60 mg/1 mL
Page 304 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
223 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.5 mg/1 mL; 100 mg/1 mL; 1 mg/1 mL; 2 mg/1 mL
224 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.5 mg/1 mL; 20 mg/1 mL; 0.5 mg/1 mL; 0.5 mg/1 mL
225 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.5 mg/1 mL; 20 mg/1 mL; 1 mg/1 mL; 0.5 mg/1 mL
226 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 0.6 mg/1 mL; 100 mg/1 mL; 1 mg/1 mL; 2.4 mg/1 mL
227 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.8 mg/1 g; 0.2 mg/1 g; 50 mg/1 g; 1 mg/1 g
228 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 0.875 mg/1 g; 0.875 mg/1 g; 50 mg/1 g; 5 mg/1 g
229 Estradiol; Estriol; Progesterone; Testosterone Cream Testosterone; Estriol; Estradiol; Progesterone 1 mg/1 g; 0.5 mg/1 g; 0.5 mg/1 g; 60 mg/1 g
230 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 100 mg/1 g; 1 mg/1 g
231 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 100 mg/1 g; 1 mg/1 g
232 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 100 mg/1 g; 2 mg/1 g
233 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 100 mg/1 g; 2 mg/1 g
234 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 100 mg/1 g; 2 mg/1 g
235 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 150 mg/1 g; 1 mg/1 g
Page 305 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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236 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 150 mg/1 g; 2 mg/1 g
237 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 150 mg/1 g; 2 mg/1 g
238 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 150 mg/1 g; 2 mg/1 g
239 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 200 mg/1 g; 2 mg/1 g
240 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 50 mg/1 g; 1 mg/1 g
241 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 1 mg/1 g; 1 mg/1 g; 60 mg/1 g; 2 mg/1 g
242 Estradiol; Estriol; Progesterone; Testosterone Cream Testosterone; Estradiol; Progesterone; Estriol 1 mg/1 mL; 0.2 mg/1 mL; 30 mg/1 mL; 0.2 mg/1 mL
243 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 1 mg/1 mL; 50 mg/1 mL; 4 mg/1 mL; 1 mg/1 mL
244 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 1 mg/1 mL; 50 mg/1 mL; 8 mg/1 mL; 1 mg/1 mL
245 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 2 mg/1 g; 2 mg/1 g; 120 mg/1 g; 4 mg/1 g
246 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 2 mg/1 g; 2 mg/1 g; 200 mg/1 g; 2 mg/1 g
247 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone 2 mg/1 g; 2 mg/1 g; 50 mg/1 g; 4 mg/1 g
248 Estradiol; Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol 2 mg/1 mL; 120 mg/1 mL; 2 mg/1 mL; 2 mg/1 mL
249 Estradiol; Estriol; Progesterone; Testosterone Cream Progesterone; Estriol; Estradiol; Testosterone 20 mg/0.5 g; 0.1 mg/0.5 g; 0.1 mg/0.5 g; 2 mg/0.5 g
Page 306 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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No. Active Ingredients Present from Listinga Dosage Form All Reported Active Ingredients All Reported Active Ingredient Strengthsb
250 Estradiol; Estriol; Progesterone; Testosterone Cream Progesterone; Estriol; Estradiol; Testosterone 20 mg/0.5 g; 0.15 mg/0.5 g; 0.15 mg/0.5 g; 2 mg/0.5 g
251 Estradiol; Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Testosterone; Progesterone 3 mg/1 mL; 1 mg/1 mL; 1 mg/1 mL; 25 mg/1 mL
252 Estradiol; Estriol; Progesterone; Testosterone Cream Progesterone; Estriol; Estradiol; Testosterone 35 mg/0.5 g; 0.25 mg/0.5 g; 0.25 mg/0.5 g; 2 mg/0.5 g
253 Estradiol; Estriol; Progesterone; Testosterone Cream Progesterone; Estriol; Estradiol; Testosterone 50 mg/0.5 g; 0.3 mg/0.5 g; 0.3 mg/0.5 g; 1.5 mg/0.5 g
254 Estradiol; Estriol; Progesterone; Testosterone Cream Progesterone; Estriol; Estradiol; Testosterone 80 mg/0.5 g; 0.25 mg/0.5 g; 0.25 mg/0.5 g; 0.25 mg/0.5 g
255 Estradiol; Estriol; Progesterone; Testosterone Solution Estradiol; Progesterone; Testosterone; Estriol 0.5 mg/1 mL; 100 mg/1 mL; 2 mg/1 mL; 2 mg/1 mL
256 Estradiol; Estriol; Pregnenolone; Progesterone Cream Estriol; Estradiol; Progesterone; Pregnenolone 2 mg/1 g; 2 mg/1 g; 40 mg/1 g; 50 mg/1 g
257 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Capsule Estriol; Estradiol; Dehydroepiandrosterone; Methyltestosterone; Progesterone 5.25 mg; 1.5 mg; 5 mg; 4 mg; 190 mg
258 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Cream Estriol; Dehydroepiandrosterone; Estradiol; Progesterone; Testosterone 0.14 mg/1 mL; 4 mg/1 mL; 0.06 mg/1 mL; 40 mg/1 mL; 1 mg/1 mL
259 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol; Dehydroepiandrosterone 0.15 mg/1 mL; 20 mg/1 mL; 4 mg/1 mL; 0.15 mg/1 mL; 10 mg/1 mL
260 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol; Dehydroepiandrosterone 0.35 mg/1 mL; 85 mg/1 mL; 0.35 mg/1 mL; 0.35 mg/1 mL; 5 mg/1 mL
Page 307 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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261 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Cream Estriol; Estradiol; Progesterone; Testosterone; Dehydroepiandrosterone 0.75 mg/1 mL; 0.25 mg/1 mL; 20 mg/1 mL; 0.5 mg/1 mL; 5 mg/1 mL
262 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Dehydroepiandrosterone; Estriol 3.75 mg/1 mL; 75 mg/1 mL; 2 mg/1 mL; 10 mg/1 mL; 2.5 mg/1 mL
263 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Cream Estradiol; Progesterone; Testosterone; Estriol; Dehydroepiandrosterone 4 mg/1 mL; 75 mg/1 mL; 2.5 mg/1 mL; 3 mg/1 mL; 15 mg/1 mL
264 Dehydroepiandrosterone; Estradiol Estriol; Progesterone; Testosterone Gel Estriol; Dehydroepiandrosterone; Estradiol; Progesterone; Testosterone 3 mg/1 mL; 30 mg/1 mL; 1.2 mg/1 mL; 50 mg/1 mL; 2 mg/1 mL
265 Estradiol Estriol; Estrone Progesterone; Testosterone Capsule Estradiol; Estriol; Estrone; Progesterone; Testosterone 2.5 mg; 100 mg; 1 mg
266 Estradiol Estriol; Estrone Progesterone; Testosterone Cream Estradiol; Estriol; Estrone; Progesterone; Testosterone

a Under “Active Ingredient Present from Listing” for combination products, methyltestosterone and testosterone enanthate are categorized as testosterone, and 7-keto-dehydroepiandrosterone as dehydroepiandrosterone.

b Under “All Reported Active Ingredient Strengths,” if field is blank, ingredient strengths and/or units were not reported.

NOTE: Resources included peer-reviewed literature on use of cBHT (e.g., IJPC, 2018), cBHT preparation adverse event reports (FDA, 2018, 2020), information provided by compounding practitioners (see the National Academies Public Access File), recent biannual outsourcing facility preparation reports (FDA, 2019), and online marketing information from compounding pharmacies.

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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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REFERENCES

FDA (U.S. Food and Drug Administration). 2018. MedWatch. https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program (accessed June 3, 2020).

FDA. 2019. Email from G. Cosel to National Academies staff regarding aggregated volume output of products containing ingredients of interest to compounded bioidentical hormone therapy study. May 30, 2020 (available through the National Academies Public Access File).

FDA. 2020. Compounding: Inspections, recalls, and other actions. https://www.fda.gov/drugs/human-drug-compounding/compounding-inspections-recalls-and-other-actions (accessed January 13, 2020).

IJPC (International Journal of Pharmaceutical Compounding). 2018. Compounding for bioidentical hormone replacement therapy patients. Purchased compiled peer-reviewed articles from 1997–2018. In IJPC. Edmond, OK: IJPC.

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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Page 307
Page 308 Cite Bookmark
Suggested Citation: "Appendix G: Compounded Bioidentical Hormone Therapy Formulations with Two or More Active Ingredients." National Academies of Sciences, Engineering, and Medicine. 2020. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. Washington, DC: The National Academies Press. doi: 10.17226/25791.
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Page 308
Next Chapter: Appendix H: Boxed Warnings on U.S. Food and Drug AdministrationApproved Estrogen and Testosterone Products
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