Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

Closed

Meeting 7 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

February 18, 2014

12:00 AM - 12:00 AM (ET)

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), John C. Bailar III, A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Thomas J. Smith, Meir Wetzler, Lauren Zeise, and Patrick Zweidler-McKay.

The following topics were discussed in the closed sessions:

1) The committee’s draft report.
2) The committee’s conclusions.
3) The project schedule.

The following materials (written documents) were made available to the committee in the closed sessions:

None.

Date of posting of Closed Session Summary:

February 24, 2014

Contact

Ricardo Payne

202.334.3982
rpayne@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Meeting 6 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

December 4 - 5, 2013

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), John C. Bailar, A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Toshihiro Shioda, Thomas J. Smith, Meir Wetzler, Lauren Zeise (via teleconference), and Patrick Zweidler-McKay.

The following topics were discussed in the closed sessions:

1. Drafts of the committee’s report.
2. The committee’s approach to the statement of task.
3. Committee and staff assignments.
4. Project schedule.

The following materials (written documents) were made available to the committee in the closed sessions:

1. Bankoff, Barbara. Bankoff Associates.
October 10, 2013.
Email to Heidi Murray-Smith, project director and Jim Reisa, board director.
Subject: New paper on N6-formyllysine.
Attachment: Dosimetry of N6-formyllysine adducts following [13C2H2] - formaldehyde exposures in rats.

2. Bankoff, Barbara. Bankoff Associates.
November 13, 2013.
Email to Heidi Murray-Smith, project director and Jim Reisa, board director.
Subject: Risk Assessment Specialty Section (RASS) Webinar: November 13, 2013.

3. Bankoff, Barbara. Bankoff Associates.
December 3, 2013.
Email to Heidi Murray-Smith, project director and Jim Reisa, board director.
Subject: Draft SRA Presentations
Attachments: Epidemiologic Evidence for Formaldehyde as a Human Leukemogen, Integrating Toxicological and Epidemiological Evidence of Carcinogenicity, and Genetic Changes in Circulating Blood Cells.

Date of posting of Closed Session Summary:

December 06, 2013

Contact

Ricardo Payne

202.334.3982
rpayne@nas.edu

Location

National Academy of Sciences Building

2101 Constitution Ave NW

Washington DC 20418, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Meeting 5 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

October 1 - 2, 2013

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), John C. Bailar, A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Toshihiro Shioda, Thomas J. Smith, Meir Wetzler, Lauren Zeise, and Patrick Zweidler-McKay (via teleconference).

The following topics were discussed in the closed sessions:

1. Drafts of the committee’s report.
2. The committee’s approach to the statement of task.
3. Assignments, project schedule, and the need for additional background materials and public sessions.

The following materials (written documents) were made available to the committee in the closed sessions:

1. Bankoff, Barbara. Bankoff Associates.
August 8, 2013.
Email to Heidi Murray-Smith, project director.
Subject: Critical Reviews in Toxicology - Analysis of 2010 Zhang et al paper with link to Gentry et al. 2013.

2. Bankoff, Barbara. Bankoff Associates.
July 25, 2013.
Email to Heidi Murray-Smith, project director and Jim Reisa, board director.
Subject: Abstracts for the SRA Session on Formaldehyde Dec. 11, 2013.

3. Bankoff, Barbara. Bankoff Associates.
August 12, 2013.
Email to Heidi Murray-Smith, project director and Jim Reisa, board director.
Subject: Second set of SRA Abstracts for December 10, 2013.

Date of posting of Closed Session Summary:

October 17, 2013

Contact

Ricardo Payne

202.334.3982
rpayne@nas.edu

Location

Arnold and Mabel Beckman Center

100 Academy Way

Irvine CA 92617, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Meeting 4

July 30 - 31, 2013

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), John C. Bailar (via teleconference), A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Toshihiro Shioda, Thomas J. Smith, Meir Wetzler, Lauren Zeise, and Patrick Zweidler-McKay.

The following topics were discussed in the closed sessions:

1. The committee’s approach to the statement of task and the report outline.
2. Drafts of the committee’s report.
3. Key studies highlighted in the National Toxicology Program’s assessment of formaldehyde
4. Pertinent literature on formaldehyde that has been identified through literature searches and public access submissions.
5. Assignments, project schedule, and the need for additional background materials and public sessions.

The following materials (written documents) were made available to the committee in the closed sessions:

1. Sass, Jennifer. Natural Resources Defense Council.
5/16/2013
Email via Current Projects System.
Subject: Judge Upholds Styrene Listing in HHS’s “Report on Carcinogens”.
Attachment: Civil Action No. 11-1079 (RBW) Document 56

2. Checkoway, Harvey. University of Washington.
Rodricks, Joseph. ENVIRON.
July 25, 2013.
Letter to Heidi Murray-Smith, project director.
Subject: Request for a Public Meeting of Scientific Experts with the Committee to Review the Formaldehyde Assessment in the NTP 12th RoC.

Date of posting of Closed Session Summary:

August 06, 2013

Contact

Ricardo Payne

202-334-3982
rpayne@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Meeting 3 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

April 30 - May 1, 2013

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Thomas J. Smith, Meir Wetzler, Lauren Zeise, and Patrick Zweidler-McKay.

The following topics were discussed in the closed sessions:

1. Guidelines for effective National Research Council advice.
2. Key studies highlighted in the National Toxicology Program’s assessment of formaldehyde.
3. Sources of pertinent information, including reviewing public access submissions and undertaking a literature search.
4. Report outline and the committee’s approach to the statement of task.
5. Assignments, project schedule, and the need for additional background materials and public sessions.

The following materials (written documents) were made available to the committee in the closed sessions:

1. Sass, Jennifer. Natural Resources Defense Council.
3/21/2013
Email via Current Projects System.
Subject: Copy of article by Jacobs, J.P. 2012. Industry group boosted political spending last year – and it paid off. E&E Publishing. Published February 7, 2012.

2. National Toxicology Program.
4/3/2013
Response to Questions Submitted by NAS.

3. Mundt, Kenneth A. ENVIRON.
4/17/2013
Email to Heidi Murray-Smith, project study director.
Attachments: Comments to NAS Committee - J. Rodricks - 19 Mar 2013, Comments to NAS Committee - C. Ward - 19 Mar 2013.

4. Mundt, Kenneth A. ENVIRON.
4/26/2013
Email to Heidi Murray-Smith, project study director.
Attachment: Rodricks letter to NAS regarding specificity of cancers - April 26 2013.

5. Mundt, Kenneth A. ENVIRON.
4/29/2013
Email to Heidi Murray-Smith, project study director.
Attachment: Letter to NAS regarding Use of Peak Exposure Metric.

6. Risotto, Steve. American Chemistry Council.
5/02/2013
Email to Heidi Murray-Smith, project director.
Subject: NTP’s RoC Review Process

Date of posting of Closed Session Summary:

May 15, 2013

Contact

Ricardo Payne

202.334.3982
rpayne@nas.edu

Location

Keck Center

500 5th St NW

Washington DC 20001, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

March 19 - 20, 2013

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), John C. Bailar III, A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Toshihiro Shioda, Thomas J. Smith, Meir Wetzler, Lauren Zeise (via teleconference), and Patrick Zweidler-McKay.

The following topics were discussed in the closed sessions:

1) Information presented during the public session.
2) The committee’s statement of task.
3) A draft report outline.
4) Writing assignments.
5) The need for speakers or additional information at future committee meetings.

The following materials (written documents) were made available to the committee in the closed sessions:

1. U.S. Department of Health and Human Services.
1/17/2013
CD containing all references from the background document for the formaldehyde assessment in the NTP 12th Report on Carcinogens.
a. List of references on CD.

2. Risotto, Steve. American Chemistry Council.
1/28/2013
Email to Heidi Murray-Smith, project study director.
Subject: Summary of recent ACC publications discussed with EPA.

3. Wolkoff, Peter. National Research Centre for the Working Environment.
2/19/2013
Email to Heidi Murray-Smith, project study director.
Attachment: Nielsen, G.D., S.T. Larsen, and P. Wolkoff. 2013. Recent trend in risk assessment of formaldehyde exposures from indoor air. Arch Toxicol. 87:73-98.

4. Sass, Jennifer. Natural Resources Defense Council.
2/25/2013
Email via Current Projects System.
Attachment: Center for Effective Government. 2013. Small Businesses, Public Health, and Scientific Integrity: Whose Interests Does the Office of Advocacy at the Small Business Administration Serve?

5. Sass, Jennifer. Natural Resources Defense Council.
2/25/2013
Email via Current Projects System.
Attachment: Center for Progressive Reform. 2013. Distorting the Interests of Small Business: How the Small Business Administration Office of Advocacy’s Politicization of Small Business Concerns Undermines Public Health and Safety.

6. Mundt, Kenneth. ENVIRON; Rodricks, Joseph. ENVIRON; Checkoway, Harvey. University of Washington; Gentry, Robinan. ENVIRON; Boffetta, Paolo. Icahn School of Medicine at Mount Sinai; Mundt, Diane. ENVIRON; Albertini, Richard. University of Vermont; and Irons, Richard. Cinpathogen, Inc. and University of Colorado Anshutz Medical Center.
3/4/2013
Letter to Heidi Murray-Smith , project study director.
Subject: Key areas and issues related to the possible leukemogenicity of formaldehyde.

7. Cox, Tony. Cox Associates and University of Colorado.
3/12/2013
Email to Heidi Murray-Smith, project study director.
Attachment: Cox Jr., L.A. Improving Causal Inferences in Risk Analysis. Forthcoming paper in Risk Analysis.

8. Risotto, Stephen. American Chemistry Council.
3/12/2013
Letter to Alfred Berg, chair of the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens
Subject: Background information for committee’s Review of the National Toxicology Program’s assessment of formaldehyde.
Attachment: Formaldehyde Science – Response to 2011 NAS Recommendations and References.

9. Risotto, Stephen. American Chemistry Council.
3/12/2013
Letter to Alfred Berg, chair of the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens
Subject: Unpublished data from NCI-funded studies of formaldehyde.

10. Jones, Wanda. U.S. Department of Health and Human Services.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC.
Title: HHS/NAS Contracts to Review Listing for Formaldehyde and Styrene in the 12th Report on Carcinogens.

11. Bucher, John. National Institute of Environmental Health Sciences.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC.
Title: Report on Carcinogens Overview.

12. Bucher, John. National Institute of Environmental Health Sciences.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC.
Title: 12th RoC Review Process and Listing Criteria.

13. Bucher, John. National Institute of Environmental Health Sciences.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC.
Title: Formaldehyde and Styrene Listings.

14. Natural Resources Defense Council.
3/19/2013
Letter to the Committee to Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens. Remarks during public comment session.

15. Bus, James, Styron.
3/19/2013
PowerPoint presentation to the Committee to Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC. Presentation during public comment session.
Title: Styrene and Styrene Oxide Animal Data.

16. Collins, James J. Dow Chemical Company.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC. Presentation during public comment session.
Title: Presentation to NAS Styrene Committee on Epidemiology.

17. Cruzan, George. Styrene Information and Research Center.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC. Presentation during public comment session.
Title: Styrene Mode of Action.

18. Goodman, Julie E. National Marine Manufacturers Association.
3/19/2013
PowerPoint presentation to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC. Presentation during public comment session.
Title: Evidence-Based Evaluation of Styrene and Human Cancer.
19. Kearns, Mary. Herban Lifestyle.
3/19/2013
Letter to the Committee to Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens. Remarks during public comment session.

20. Scranton, Alexandra. Women's Voices for the Earth.
3/19/2013.
Email via Current Projects System.
Subject: Comments on review of styrene and formaldehyde assessments

21. Risotto, Steve, American Chemistry Council.
3/19/2013
PowerPoint slide to the Committee to Review the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens and the Committee to Review the Styrene Assessment in the National Toxicology Program 12th Report on Carcinogens in Washington, DC. Presented during public comment session.
Slide Subject: NPC - NCI’s Highest Peak Exposure Association Driven by Plant 1.

22. Collins, James. Dow Chemical Company.
3/20/2013
Email to Heidi Murray Smith, project study director.
Attachment: Collins and Bodner (2012). Cancer Mortality of Workers Exposed to Styrene in the US Reinforced Plastics and Composite Industry.

23. Risotto, Steve. American Chemistry Council
3/20/2013
Email to Heidi Murray-Smith, project study director.
Attachment: ACC’s Formaldehyde Panel Comments for the NAS RoC Committee.

Date of posting of Closed Session Summary:

March 26, 2013

Contact

Ricardo Payne

202.334.3982
rpayne@nas.edu

Location

Keck Center

500 5th St NW

Washington DC 20001, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

February 20, 2013

12:00 AM - 12:00 AM (ET)

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Alfred O. Berg (chair), John C. Bailar III, A. Jay Gandolfi, David Kriebel, John B. Morris, Kent E. Pinkerton, Ivan Rusyn, Toshihiro Shioda, Thomas J. Smith, Meir Wetzler, Lauren Zeise, and Patrick Zweidler-McKay.

The following topics were discussed in the closed sessions:

1) The committee’s bias and conflict of interest discussion.
2) Logistics in preparation for the March 19-20 committee meeting.

The following materials (written documents) were made available to the committee in the closed sessions:

None.

Date of posting of Closed Session Summary:

February 21, 2013

Contact

Ricardo Payne

202.334.3982
rpayne@nas.edu

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

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Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

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Meeting 7 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

Meeting 6 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

Meeting 5 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

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Meeting 3 - Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens

Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens