Our Work

Our Work Consensus/Advisory Activity Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for New Approach Methods (NAMs) for use in Human Health Risk Assessment

Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for New Approach Methods (NAMs) for use in Human Health Risk Assessment

Completed

Topics

Environment and Biology

Animal testing is often used to evaluate the potential risks, uses, and environmental impacts of chemicals. New Approach Methodologies (NAMs) are technologies and approaches that can potentially provide the same hazard and risk assessment information without the use of animal testing. To further establish scientific confidence in these approaches, this study will review the variability and relevance of existing mammalian toxicity tests, specifically when it comes to human health risk assessment. The goal of this study is to set data-driven and science-based expectations for NAMs based on the variability and relevance of the traditional toxicity testing models.

New Report Recommends EPA Develop Framework for Evaluating New Approach Methods for Toxicity Testing Jun 16, 2023 Media Advisory

About Publications/Resources Past Events

Events

Public Release Webinar: Building Confidence in New Evidence Streams for Human Health Risk Assessment

June 16, 2023
2:00 PM - 3:00 PM (EDT)

Webinar
Past

The National Academies of Sciences, Engineering, and Medicine invites you to a public release webinar of a new report on Friday, June 16, 2023 from 2:00 - 3:00 PM ET. The report, Building Confidence i...

New Approach Methods (NAMs) for Human Health Risk Assessment | Workshop 2

May 12, 2022
11:00 AM - 4:00 PM (EDT)

Workshop
Past

MEETING OVERVIEW Animal testing is often used to evaluate the potential risks, uses, and environmental impacts of chemicals. New Approach Methods (NAMs) are technologies and approaches (including comp...

New Approach Methods (NAMs) for Human Health Risk Assessment | Workshop 1

December 9, 2021
10:00 AM - 3:00 PM (EST)

Workshop
Past

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 1

September 23, 2021
1:00 PM - 5:00 PM (EDT)

Webinar
Past

This first meeting of the committee will include open and closed sessions. The open session will include discussions with EPA staff regarding the statement of task, reasons for the study, and descript...

Meetings

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 23

April 11 - 12, 2023

Closed
Past

This meeting is closed in its entirety. The closed session will be used to discuss the draft report. Timing: 9am - 5:30pm PT on 4/11, 9am - 1pm PT on 4/12

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 22

April 6, 2023
12:30 PM - 1:30 PM (EDT)

Closed
Past

This meeting is closed in its entirety. The closed session will be used to discuss the draft report.

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 21

February 16, 2023
12:00 PM - 3:00 PM (EST)

Closed
Past

This meeting is closed in its entirety. The closed session will be used to discuss the draft report.

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 20

February 2, 2023
3:00 PM - 5:00 PM (EST)

Closed
Past

This meeting is closed in its entirety. The closed session will be used to discuss the draft report.

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 19

January 26, 2023
12:00 PM - 2:00 PM (EST)

Closed
Past

This meeting is closed in its entirety. The closed session will be used to discuss the draft report.

Subscribe to Email from the National Academies

Keep up with all of the activities, publications, and events by subscribing to free updates by email.

Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for New Approach Methods (NAMs) for use in Human Health Risk Assessment

Public Release Webinar: Building Confidence in New Evidence Streams for Human Health Risk Assessment

New Approach Methods (NAMs) for Human Health Risk Assessment | Workshop 2

New Approach Methods (NAMs) for Human Health Risk Assessment | Workshop 1

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 1

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 23

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 22

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 21

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 20

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 19

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 18

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 17

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 16

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 15

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 14

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 13

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 12

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 11

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 10

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 9

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 8

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 7

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 6

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 5

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 4

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 3

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 2

My Academies

Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for New Approach Methods (NAMs) for use in Human Health Risk Assessment

Dropdown items

Public Release Webinar: Building Confidence in New Evidence Streams for Human Health Risk Assessment

New Approach Methods (NAMs) for Human Health Risk Assessment | Workshop 2

New Approach Methods (NAMs) for Human Health Risk Assessment | Workshop 1

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 1

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 23

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 22

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 21

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 20

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 19

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 18

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 17

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 16

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 15

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 14

New Approach Methods (NAMs) for use in Human Health Risk Assessment | Meeting 13

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 12

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 11

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 10

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 9

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 8

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 7

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 6

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 5

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 4

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 3

New Approach Methods (NAMs) for Human Health Risk Assessment | Meeting 2