This workshop explored the nuanced nature of trust in science – what the elements of trust are, and how trust is built, maintained, or lost. Geared for the life science community, the workshop featured many scholars and journalists at the forefront of science communication, political science, and ethics. Speakers examined the constituent components of trust, conditions in which public trust in science is broad, and conditions in which trust in science may be compromised. Through breakout sessions, participants discussed the circumstances that contrain or enhance public trust of life sciences issues and ideas for building, maintaining, or restoring trust.