Previous Chapter: Appendix A: Details in Support of the Risk Exemplar in Chapter 6
Suggested Citation: "Appendix B: Computation of Average Daily Dose." National Research Council. 2012. Water Reuse: Potential for Expanding the Nation's Water Supply Through Reuse of Municipal Wastewater. Washington, DC: The National Academies Press. doi: 10.17226/13303.

Appendix B

Computation of Average Daily Dose

The Average Daily Dose from all exposures to reclaimed water (ADDRW) can be estimated using the following equation (modified from Hutcheson et al., 1990):

ADDRW = ADDR + ADDD + ADDI

The Average Daily Dose from ingestion of the reclaimed water (ADDR) can be estimated using the following equation (modified from Hutcheson and Martin, 1992):

image

where

 
  ContaminantR = Concentration of chemical in reclaimed water (mass/volume),
  VI = Daily volume of reclaimed water ingestion (mass/volume),
  BAF = Bioavailability adjustment factor,
  D2 = Duration of the exposure period (time),
  BW = Average body weight (e.g., 70 kg),
  AP = Averaging period (time),
  C = Appropriate units conversion factor.

The Average Daily Dose from dermal contact with reclaimed water (ADDD) can be estimated using the following equation:

image

where

 
  ContaminantR = Concentration of chemical in reclaimed water (mass/volume),
  SA = Skin surface area in contact with the surface water during the period of exposure (area),
  PC = Permeability constant (volume/time × area),
  D1 = Average duration of each exposure event (time/event),
  D2 = Duration of the exposure period (time),
  BAF = Bioavailability adjustment factor,
  F = Number of exposure events during the exposure period divided by the number of days in the exposure period (events/time),
  D1 = Average duration of each exposure event (time/event),
  D2 = Duration of the exposure period (time),
  BW = Average body weight (e.g., 70 kg),
  AP = Averaging period (time),
  C = Appropriate units conversion factor.
Suggested Citation: "Appendix B: Computation of Average Daily Dose." National Research Council. 2012. Water Reuse: Potential for Expanding the Nation's Water Supply Through Reuse of Municipal Wastewater. Washington, DC: The National Academies Press. doi: 10.17226/13303.

The Average Daily Dose from inhalation of contaminants in reclaimed water (ADDI) can be estimated using the following equation:

image

where

ContaminantR = Concentration of chemical in reclaimed water (mass/volume),
VR = Daily respiratory volume during the period of exposure (volume/time),
BAF = Bioavailability adjustment factor,
F = Number of exposure events during the exposure period divided by the number of days in the exposure period (events/time),
D1 = Average duration of each exposure event (time/event),
D2 = Duration of the exposure period (time),
BW = Average body weight (e.g., 70 kg),
AP = Averaging period (time),
C = Appropriate units conversion factor.
Suggested Citation: "Appendix B: Computation of Average Daily Dose." National Research Council. 2012. Water Reuse: Potential for Expanding the Nation's Water Supply Through Reuse of Municipal Wastewater. Washington, DC: The National Academies Press. doi: 10.17226/13303.
Page 249
Suggested Citation: "Appendix B: Computation of Average Daily Dose." National Research Council. 2012. Water Reuse: Potential for Expanding the Nation's Water Supply Through Reuse of Municipal Wastewater. Washington, DC: The National Academies Press. doi: 10.17226/13303.
Page 250
Next Chapter: Appendix C: Survey of Water Reclamation Costs
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