| AHRQ |
Agency for Healthcare Research and Quality |
| ANPRM |
Advanced Notice of Proposed Rulemaking |
| CLIA |
Clinical Laboratory Improvement Amendments |
| CRT |
cluster randomized trial |
| CSER |
Clinical Sequencing Exploratory Research |
| EHR |
electronic health record |
| eMERGE |
Electronic Medical Records and Genomics |
| FIPP |
Fair Information Practice Principle |
| HHS |
U.S. Department of Health and Human Services |
| HIPAA |
Health Insurance Portability and Accountability Act |
| HITECH |
Health Information Technology for Economic and Clinical Health |
| IRB |
institutional review board |
| IT |
information technology |
| LHCS |
learning health care system |
| NCI |
National Cancer Institute |
| NCI CIRB |
National Cancer Institute Central Institutional Review Board |
| NIH |
National Institutes of Health |
| OHRP |
Office for Human Research Protections |
| PEER |
Platform for Engaging Everyone Responsibly |
| PHI |
Protected Health Information |
| SACHRP |
Secretary’s Advisory Committee on Human Research Protections |
| TCGA |
The Cancer Genome Atlas |