Progress Toward Transforming the Integrated Risk Information System (IRIS) Program: A 2018 Evaluation (2018)
Chapter: Front Matter
Progress Toward Transforming the
Integrated Risk Information System (IRIS) Program:
A 2018 Evaluation
Committee to Review Advances Made to the IRIS Process
Board on Environmental Studies and Toxicology
Division on Earth and Life Studies
A Consensus Study Report of
THE NATIONAL ACADEMIES PRESS
Washington, DC
www.nap.edu
THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001
This project was supported by Contract EP-C-14-005, TO#008 between the National Academies of Sciences, Engineering, and Medicine and the US Environmental Protection Agency. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the view of any organization or agency that provided support for this project.
Digital Object Identifier: https://doi.org/10.17226/25086
Copyright 2018 by the National Academy of Sciences. All rights reserved.
Printed in the United States of America
Suggested citation: National Academies of Sciences, Engineering, and Medicine. 2018. Progress Toward Transforming the Integrated Risk Information System (IRIS) Program: A 2018 Evaluation. Washington, DC: The National Academies Press. doi: https://doi.org/10.17226/25086.
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COMMITTEE TO REVIEW ADVANCES MADE TO THE IRIS PROCESS
Members
JONATHAN M. SAMET (Chair), Colorado School of Public Health, Denver, CO
RICHARD A. CORLEY (retired), Pacific Northwest National Laboratories, Richland, WA
GEORGE DASTON, Proctor & Gamble Company, Cincinnati, OH
DAVID C. DORMAN, North Carolina State University, Raleigh, NC
RUSS B. HAUSER, Harvard T.H. Chan School of Public Health, Boston, MA
KAREN A. ROBINSON, Johns Hopkins University, Baltimore, MD
RICHARD P. SCHEINES, Carnegie Mellon University, Pittsburgh, PA
LAUREN ZEISE, CalEPA Office of Environmental Health Hazard Assessment, Berkeley, CA
YILIANG ZHU, University of New Mexico, Albuquerque, NM
Staff
ELLEN K. MANTUS, Project Director
RADIAH ROSE-CRAWFORD, Manager, Editorial Projects
SUZANNE THILENIUS, Administrative Coordinator
MIRSADA KARALIC-LONCAREVIC, Manager, Technical Information Center
JESSICA WOLFMAN, Senior Program Assistant
Sponsor
US ENVIRONMENTAL PROTECTION AGENCY
BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY
Members
WILLIAM H. FARLAND (Chair), Colorado State University, Fort Collins, CO
RICHARD A. BECKER, American Chemistry Council, Washington, DC
E. WILLIAM COLGLAZIER, American Association for the Advancement of Science, Washington, DC
DOMINIC M. DITORO, University of Delaware, Newark, DE
DAVID C. DORMAN, North Carolina State University, Raleigh, NC
CHARLES T. DRISCOLL, JR., Syracuse University, Syracuse, NY
ANNE FAIRBROTHER, Exponent, Inc., Philomath, OR
GEORGE GRAY, The George Washington University, Washington, DC
STEVEN P. HAMBURG, Environmental Defense Fund, New York, NY
ROBERT A. HIATT, University of California, San Francisco, CA
SAMUEL KACEW, University of Ottawa, Ontario, Canada
H. SCOTT MATTHEWS, Carnegie Mellon University, Pittsburgh, PA
ROBERT PERCIASEPE, Center for Climate and Energy Solutions, Arlington, VA
R. CRAIG POSTLEWAITE, US Department of Defense, Burke, VA
MARK A. RATNER, Northwestern University, Evanston, IL
JOAN B. ROSE, Michigan State University, East Lansing, MI
GINA M. SOLOMON, California Environmental Protection Agency, Sacramento, CA
ROBERT M. SUSSMAN, Sussman and Associates, Washington, DC
DEBORAH L. SWACKHAMER, University of Minnesota, St. Paul, MN
PETER S. THORNE, University of Iowa, Iowa City, IA
Staff
TERESA A. FRYBERGER, Director
ELLEN K. MANTUS, Scholar and Director of Risk Assessment
RAYMOND A. WASSEL, Scholar and Director of Environmental Studies
SUSAN N.J. MARTEL, Senior Program Officer for Toxicology
ELIZABETH BOYLE, Program Officer
TAMARA DAWSON, Program Associate
BERNIDEAN WILLIAMS-SMITH, Financial Associate
SUZANNE THILENIUS, Administrative Coordinator
JESSICA WOLFMAN, Senior Program Assistant
Acknowledgments
This Consensus Study Report was reviewed in draft form by persons chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the National Academies of Sciences, Engineering, and Medicine in making each published report as sound as possible and to ensure that it meets institutional standards of quality, objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process.
We thank the following for their review of this report:
David Eaton, University of Washington
David Savitz, Brown University
Joyce Tsuji, Exponent
Harvey Clewell, Ramboll
Lisa Bero, University of Sidney
Nancy Reid, University of Toronto
Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations of this report, nor did they see the final draft before its release. The review of the report was overseen by Mark Cullen, Stanford University, who was responsible for making certain that an independent examination of the report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content rests entirely with the authoring committee and the National Academies.
The committee gratefully acknowledges the staff of the US Environmental Protection Agency, especially Tina Bahadori and Kristina Thayer, for their presentations to the committee during open sessions. The committee is also grateful for the assistance of Norman Grossblatt who served as the report editor.
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Contents
The Integrated Risk Information System and Previous National Academies Reports
The Committee, Its Task, and Its Approach
2 RESPONSES TO NATIONAL ACADEMIES RECOMMENDATIONS
APPENDIXES
A BIOGRAPHIC INFORMATION ON THE COMMITTEE TO REVIEW ADVANCES MADE TO THE IRIS PROCESS
C PRESENTATIONS BY US ENVIRONMENTAL PROTECTION AGENCY
D POSTERS BY US ENVIRONMENTAL PROTECTION AGENCY
E FINDINGS REGARDING INDIVIDUAL RECOMMENDATIONS
BOXES AND FIGURE
BOXES
2-1 Environmental Protection Agency Description of Its Portfolio Approach
FIGURE
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