An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine will examine the current evidence and develop a principles-based, context-responsive framework (or “Roadmap”) to guide health-centered climate action that is globally relevant and locally adaptable. The Roadmap will seek to identify transformative strategies that prioritize improvements in population health, equity, and well-being, while supporting inclusive economic resilience and fiscal sustainability, recognizing these as core pillars for building sustainable, climate resilient societies within planetary boundaries.

Using systems thinking to assess interdependencies across sectors and scales, the committee will review and examine the evidence to:

· Assess how structural and contextual factors (e.g., governance structures, availability of financial resources, climate vulnerability, health system capacity) shape the feasibility, sequencing, pace, and distributional impacts of systems transformation to improve population health and advance health for all within the context of net-zero transitions. This will include attention to approaches that align economic and financial systems with societal well-being, equity, and sustainability.

· Identify strategic leverage (or entry) points within and across the highest-emitting economic sectors (e.g., energy; heavy industry; agriculture, forestry, and other land use [AFOLU]; transportation) where systemic shifts can most effectively enhance population health and well-being, while delivering co-benefits for climate resilience and long-term economic sustainability.

· Examine how current measurement and evaluation frameworks capture systems-level change and climate-health co-benefits, and identify opportunities to strengthen their relevance, credibility, and usability across diverse national and regional contexts.

Informed by several case examples across national and regional scales that include different economic sectors, the committee will develop strategic, actionable recommendations to support the implementation of transformation efforts aimed at achieving health for all at net-zero emissions. Where evidence is limited or does not yet exist, the committee will draw on its collective expertise and best judgment to inform its recommendations.