Refinements to the Methods for Developing Spacecraft Exposure Guidelines (2016)

Chapter: Appendix B: Example Report Outlines for Future SMAC and SWEG Documents

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF.
Previous Chapter: Appendix A: Biographical Information on the Committee on Spacecraft Exposure Guidelines
Page 48 Cite Bookmark
Suggested Citation: "Appendix B: Example Report Outlines for Future SMAC and SWEG Documents." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
Save
Cancel

Appendix B

Example Report Outlines for Future SMAC and SWEG Documents

OUTLINE FOR NEW CHEMICALS

  1. Physical and Chemical Properties
  2. Occurrence, Source, and Use on Spacecraft
  3. Toxicokinetics
  4. Toxicodynamics and Mechanism of Action
  5. Toxicity Summary
    1. Literature Search Strategy (summary of databases, dates, search terms, etc.)
    2. Acute Toxicity
      1. Human
      2. Animal
    3. Short-Term Toxicity
      1. Human
      2. Animal
    4. Subchronic Toxicity
      1. Human
      2. Animal
    5. Chronic Toxicity
      1. Human
      2. Animal
    6. Interaction with Other Chemicals
    7. Spaceflight Effects
  6. Rationale for Acceptable Concentrations
    1. Description of How Each SMAC/SWEG Was Derived (to include detailed justification of the selection of health end points, key studies, point of departure, and uncertainty factors)
    2. Exposure Standards Set by Other Organizations
  7. Research Recommendations
Page 49 Cite Bookmark
Suggested Citation: "Appendix B: Example Report Outlines for Future SMAC and SWEG Documents." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
Save
Cancel

OUTLINE FOR UPDATING CHEMICAL GUIDELINES

  1. Occurrence, Source, and Use on Spacecraft
  2. Summary of Original Approach to Setting SMACs or SWEGs
  3. New Data
    1. Literature Search Strategy (databases, dates, search terms, etc.)
    2. Toxicokinetics
    3. Toxicodynamics and Mechanism of Action
    4. Acute Toxicity
    5. Short-Term Toxicity
    6. Subchronic Toxicity
    7. Chronic Toxicity
    8. Interaction with Other Chemicals
    9. Spaceflight Effects
  4. Rationale for Revision to the Original SMACs or SWEGs
    1. Description of Revisions to Each SMAC/SWEG (to include detailed justification of the selection of health end points, key studies, point of departure, and uncertainty factors)
    2. Exposure Standards Set by Other Organizations
  5. Research Recommendations
Page 50 Cite Bookmark
Suggested Citation: "Appendix B: Example Report Outlines for Future SMAC and SWEG Documents." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
Save
Cancel

This page intentionally left blank.

Page 48 Cite Bookmark
Suggested Citation: "Appendix B: Example Report Outlines for Future SMAC and SWEG Documents." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
Save
Cancel
Page 48
Page 49 Cite Bookmark
Suggested Citation: "Appendix B: Example Report Outlines for Future SMAC and SWEG Documents." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
Save
Cancel
Page 49
Page 50 Cite Bookmark
Suggested Citation: "Appendix B: Example Report Outlines for Future SMAC and SWEG Documents." National Academies of Sciences, Engineering, and Medicine. 2016. Refinements to the Methods for Developing Spacecraft Exposure Guidelines. Washington, DC: The National Academies Press. doi: 10.17226/21888.
Save
Cancel
Page 50
Subscribe to Emails from the National Academies
Stay up to date on activities, publications, and events by subscribing to email updates.