Sickle Cell Disease in Social Security Disability Evaluations (2025)

Chapter: 6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System

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Previous Chapter: 5 Effects of Sickle Cell Disease on the Central Nervous System
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 148 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 149 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 151 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 152 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 154 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 155 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 156 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 157 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 159 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 160 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 161 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 162 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 163 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 165 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 166 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 167 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 168 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 169 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 169
Page 170 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 171 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 171
Page 172 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 173 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 173
Page 174 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 175 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 176 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 177 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 178 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 179 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Page 179
Page 180 Cite
Suggested Citation: "6 Effects of Sickle Cell Disease on Body Systems Other Than the Central Nervous System." National Academies of Sciences, Engineering, and Medicine. 2025. Sickle Cell Disease in Social Security Disability Evaluations. Washington, DC: The National Academies Press. doi: 10.17226/29319.
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Next Chapter: 7 Cumulative Burden of Living with Sickle Cell Disease
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