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Assessing the Burden and Potential Strategies to Address Antimicrobial Resistance: A Workshop

Completed

There is broad recognition of the need to address the development and spread of antimicrobial resistance (AMR). A global, systematic analysis estimates that AMR infections lead to 1.27- 4.95 million deaths per year, and resistant bacterial infections are now a leading cause of neonatal mortality worldwide. However, a critical question remains on whether the impact of AMR is being fully understood and quantified throughout medical practice and everyday life, from cancer treatment to food production. Discussions at this workshop will cover current clinical and economic burdens of AMR, data availability and analytical methods, and potential strategies to incorporate these insights.

Description

A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize a public workshop to explore the current burden of antimicrobial resistance and discuss opportunities for future policies in the context of new scientific innovations and potential disruptions from proposed and pilot incentive mechanisms. The workshop will feature invited presentations and discussions that may consider topics, including:

  1. Assessment of the current clinical and economic burden of antimicrobial resistance, including an overview of emerging challenges, efforts to improve data availability and analytical methods, and examination of the impact antimicrobials have as the foundation of modern medicine and their role in strengthening public health preparedness and response to health emergencies.
  2. Highlights in scientific progress in developing new therapeutics to address antimicrobial resistant pathogens, including discussions around technical challenges, financial costs, and market viability.
  3. Innovative incentive models and policy options (proposed or pilot programs) that address antimicrobial resistance, including discussions around: barriers for implementation and how these barriers may be overcome, how incentives mechanisms can be adapted to national or regional contexts, how these approaches might complement each other, and considerations of roll out of and sustainable access to novel antimicrobial agents.

The planning committee will organize the workshop, develop the agenda, select speakers and discussants, and moderate or identify moderators for the discussions. A proceedings summarizing the presentations and discussions held during this workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Contributors

Committee

Chair

Member

Member

Member

Member

Member

Member

Member

Sponsors

American Society of Tropical Medicine and Hygiene

Burroughs Wellcome Fund

Centers for Disease Control and Prevention (CDC)

Department of Veterans Affairs

EcoHealth Alliance

Infectious Diseases Society of America

Johnson & Johnson

Merck & Co., Inc.

National Institute of Allergy and Infectious Diseases

New Venture Fund

Other, Federal

Private: For Profit

Private: Non Profit

Rockefeller-Foundation

Sanofi

Society of Infectious Diseases Pharmacists

Uniformed Services University of the Health Sciences

United States Agency for International Development

Staff

Julie Liao

Lead

Julie Pavlin

Liz Ashby

Claire Biffl

Taylor Windmiller

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