Population surveys collect information from participants by asking questions. Today, many surveys also collect biologic specimens that can be used to analyze a respondent's DNA and other biomarkers. The National Health and Nutrition Examination Survey (NHANES) administers a physical examination, collects biospecimens, and reports some test results (e.g., cholesterol levels) to the participant. Traditionally, NHANES participants have been told that they will not be contacted with personal genetic results. However, clinical science is evolving to encourage more return of individual research results. Therefore, NHANES will revisit the issue of if, when, and how to return genetic results to study participants.