A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize and execute a public 1.5 to 2-day workshop to present and discuss issues in returning results from genome analysis from the National Health and Nutrition Examination Survey (NHANES) and other population surveys. The workshop will bring together geneticists, bioethicists, clinicians, genetic counselors, survey methodologists, and behavioral and social scientists, as well as public health and other experts to examine relevant issues, such as:

• Explore the feasibility of returning genomic results to NHANES participants given certain operational constraints;
• Identify models and current practices for returning clinically actionable genomic results that could inform approaches for population surveys;
• Identify current practices to incorporate clinically actionable genomic results into informed consent;
• Describe the scope of state-of-the-art genomic technologies that could be or are being applied in population surveys and the potential contributions of different types of genomic data (e.g., genotyping vs. sequencing);
• Identify current practices for conducting analyses of NHANES genomic survey data including anonymization and access to data by public health and other researchers which aligns with National Center for Health Statistics Data Release Policy; and
• Identify current practices in the return of results of other “omic” fields (i.e., microbiome, transcriptomics, proteomics) and epigenetics in NHANES.

The planning committee will define the specific topics to be addressed, develop the agenda, and select and invite speakers and other participants. Following the event, a proceedings of the workshop will be produced in accordance with institutional guidelines.