An NRC committee will assess EPA’s highest priority needs for mission-relevant laboratory science and technical support, now and during the next ten years. Recognizing the need to operate within budget constraints and growing demands, and recognizing the potential contributions of external sources of scientific information from other government agencies, industry, and academia in the U.S. and other nations, the committee will develop principles for the efficient and effective management of EPA’s laboratory enterprise to meet the agency’s mission needs and strategic goals.