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DOD needs to understand the relative threat of the increasingly long list of registered chemical substances, particularly in terms of potential acute hazard. To help DOD achieve its goal to protect its deployed personnel, this study will consider modern approaches for predicting toxicity and suggest an overall conceptual approach for using such information to evaluate acute hazards. The committee will consider the information provided by predictive-toxicology approaches that is increasingly being generated and used in the environmental health and pharmaceutical sectors to enhance or replace information from traditional, empirical testing of chemical safety in animals.
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Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense
Consensus Study Report
ยท2015
The US Department of Defense (DOD) is faced with an overwhelming task in evaluating chemicals that could potentially pose a threat to its deployed personnel. There are over 84,000 registered chemicals, and testing them with traditional toxicity-testing methods is not feasible in terms of time or mon...
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