Careful observation, data collection, analysis, and presentation of uncertainty are key to application of the scientific method and conduct of science. However, the use of animals in science often elicits strong emotions and responses from the public. This workshop will focus on enhancing public understanding of the scientific method in animal research, caring for animals during scientific work, and the contributions of animal research to improve animal and human health. The planning committee will explore effective communication methods, ways to integrate information from scientists into media for diverse public audiences, assessing successful communication, and addressing challenges in understanding animal research.