A planning committee of the National Academies of Sciences, Engineering, and Medicine will organize a series of five short virtual workshops to consider opportunities for cross-sector collaboration and partnership across science and technology disciplines to enhance the United States’ approach to addressing climate change. The workshops will explore ongoing and new opportunities to leverage science and technology solutions to inform the development of climate policy, and will examine the impacts of climate policy on economic development, inequality, and international competitiveness. Topics for consideration during the workshops include the state of U.S. climate science infrastructure; the clean energy transition; technologies for deep decarbonization; the social cost of carbon; and climate impacts on the intersection of health, equity, and security. The virtual workshops – each 90 minutes in length – are meant to catalyze high-level policy discussions and to stimulate further dialogue on cross-cutting science and innovation policy issues. A rapporteur-authored proceedings in brief will be published summarizing all workshops in the series.