Review of NASA's Longitudinal Study of Astronaut Health (2004)
Chapter: Appendix B: Variables in the LSAH Database
B
Variables in the LSAH Database
Physical Examination
Vital signs: Sitting, standing and recumbent blood pressure and pulse, height, weight, percent body fat (based on sum of four skinfolds), temperature
Clinical evaluation: Review of systems, significant interval history, summary of defects and diagnoses, recommendations, qualifying information
Dental exam results
Vision (full exam): Corrected and uncorrected distant and near vision, each eye and binocular; color vision, depth perception, heterophorias, intraocular pressure; only near and distant acuity tested for comparison participants
Audiometry: 500, 1,000, 2,000, 3,000, 4,000, 6,000, 8,000 Hz for each ear
ECG: Consultant interpretation
Pulmonary function test: Standard spirometry test
Dual energy X-ray absorptiometry (DEXA) scan
Exercise tolerance test (85% max): Bruce Protocol - heart rate and blood pressure recorded under the following conditions: every minute for 5 minutes in supine position, every minute for 3 minutes standing, immediately after running in place and every minute for 3 minutes, every minute for 3 minutes at each of the following grade/mph: 10/1.7, 12/2.5, 14/3.4, 16/4.2, 18/5.0, 20/5.5, 22/6.0, and during recovery every minute until return to baseline, total exercise time, reason test terminated early
Chest X-ray interpretation
Proctosigmoidoscopy interpretation
Colonoscopy interpretation
Mammogram consultant interpretation
Pelvic exam/Pap smear; pathology report
Comprehensive Laboratory Analysis
Hematology: WBC, RBC, hemoglobin, hematocrit, MCV, MCH, MCHC, platelet count, RDW, reticulocyte count, differential (neutrophils, lymphocytes, monocytes, basophils, eosinophils)
Chemistry panel: Glucose, BUN, uric acid, creatinine, total bilirubin, aspartate transaminase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, glutamyltransferase, sodium, potassium, chloride, phosphorus, calcium, magnesium, carbon dioxide, total protein
Serum iron: Iron, ferritin, total iron binding capacity, transferrin, transferrin saturation
Lipid profile: Cholesterol, triglyceride, VLDL, HDL, LDL, Chol/HLD ratio
Urinalysis: pH, specific gravity, color, appearance, protein, glucose, ketone, blood, bilirubin, urobilinogen, nitrite, leukocyte esterase, WBC, RBC, epithelial cells, mucus
Ionized calcium profile: Ionized calcium, ionized calcium at 7.40
SPE panel: Total protein, albumin, alpha 1, alpha 2, beta, gamma, A/G ratio
Immunoglobulin panel: IGG, IGA, IGM, IGE
Serology: Hepatitis A total, hepatitis B surface antigen, hepatitis B surface antibody, hepatitis C antibody, RPR, CRP, anti-HIV
Thyroid function tests
Personal Medical History
Self-report of personal medical history, checklist review of medical problems, hospitalizations
Medical Records Obtained from the Johnson Space Center Medical Clinics, Private Physicians and Hospitals
Acute and chronic medical events, diagnoses, medical procedures, treatment, medications, recommendations
Lifestyle Questionnaire
Marital status and history, family medical history, reproductive history, smoking history, alcohol use, exercise and weight patterns, pilot experience, hormone use (women only)
Death Records
Death certificate, hospitalization records, and autopsy reports, if available, are obtained
