Biosocial Surveys (2008)

Chapter: 16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim

Previous Chapter: 15 Genoeconomics--Daniel J. Benjamin, Christopher F. Chabris, Edward L. Glaeser, Vilmundur Gudnason, Tamara B. Harris, David I. Laibson, Lenore J. Launer, and Shaun Purcell
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
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Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 337
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
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Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
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Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
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Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 341
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 342
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 343
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 344
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
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Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 346
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 347
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 348
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 349
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 350
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 351
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 352
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 353
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 354
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 355
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 356
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 357
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 358
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 359
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 360
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 361
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 362
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 363
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 364
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 365
Suggested Citation: "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." National Research Council. 2008. Biosocial Surveys. Washington, DC: The National Academies Press. doi: 10.17226/11939.
Page 366
Next Chapter: 17 Multilevel Investigations: Conceptual Mappings and Perspectives--John T. Cacioppo, Gary G. Berntson, and Ronald A. Thisted
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