The committee used the points below to help guide its review of the proposals. The reviewers were asked to comment on the strengths and weaknesses of the proposals by considering the following:
Level of scientific merit
Potential to advance understanding of an important problem or question in the field; potential for breakthrough science resulting in new discoveries and understanding
Impact that successful completion of the proposed research would have on the knowledge, methods, and current barriers in the field
Project is scientifically and technologically feasible with clear, well-developed, and appropriate goals, objectives, and approach to the proposed studies
Justification for requested time allocation
Clear and well-justified need for multi-microsecond simulation time Clear and convincing justification that the length and number of proposed simulation runs and node-hours requested are necessary and sufficient to achieve the scientific objectives
Investigator qualifications and past accomplishments
Appropriate experience and training to successfully conduct the proposed studies
Evidence of knowledge and prior experience with molecular simulations
Past publications