The Science and Applications of Synthetic and Systems Biology: Workshop Summary (2011)
Chapter: Appendix B: Agenda
The Science and Applications of Synthetic and Systems Biology
March 14-15, 2011
Keck Building, Room 100
500 Fifth Street, NW
Washington, DC
DAY 1: MONDAY, MARCH 14, 2011 | |
8:00–8:30 am | Registration and Continental Breakfast |
8:30–8:45 am | Welcoming Remarks David Relman, M.D., Chair, and Jim Hughes, M.D., and Lonnie King, D.V.M., Vice-Chairs, Forum on Microbial Threats |
8:45–9:30 am | Keynote Remarks David Relman, Moderator Synthetic Biology and Biodefense Andrew Ellington, Ph.D., University of Texas at Austin |
9:30–10:00 am | Discussion |
10:00–10:15 am | Break |
SESSION 1: The Promise of Synthetic and Systems Biology for the Understanding and Management of Infectious Diseases | |
10:15–10:45 am | Synthetic biology, systems biology, and microbial threats James J. Collins, Ph.D., Boston University |
10:45–11:15 am | A metabolic engineering platform for discovery and production of new therapeutics Greg Stephanopoulos, Ph.D., Massachusetts Institute of Technology (MIT) |
11:15–11:45 am | Insights into pathogen-host interactions from systems biology Bernhard Palsson, Ph.D., University of California, San Diego |
11:45–12:15 pm | Commercial applications of synthetic biology David Berry, M.D., Ph.D., Flagship Ventures |
12:15–12:45 pm | Discussion |
12:45–1:30 pm | Lunch |
SESSION 2: “The Basics” of Synthetic Biology: Bottom-Up vs. Top-Down Approaches | |
1:30–2:00 pm | Systems for synthetic biology Hans Westerhoff, Ph.D., University of Manchester and the VU University Amsterdam |
2:00–2:30 pm | Design and complexity Herbert Sauro, Ph.D., University of Washington |
2:30–3:00 pm | DNA synthesis George Church, Ph.D., Harvard University |
3:00–3:30 pm | Synthetic biology “from scratch” Gerald Joyce, M.D., Ph.D., The Scripps Research Institute |
3:30–3:45 pm | Break |
3:45–4:15pm | Protein engineering and high throughput immune function analyses for the discovery of the next generation of protein therapeutics George Georgiou, Ph.D., University of Texas at Austin |
4: 15–4:45 pm | Synthesis and installation of genomes Clyde Hutchison III, Ph.D., J. Craig Venter Institute |
4:45–5:15 pm | Access through refactoring: Rebuilding complex functions from the ground up Chris Voigt, Ph.D., University of California, San Francisco |
5:15–6:00 pm | Discussion |
6:00 pm | Meeting Adjourns |
DAY 2: TUESDAY, MARCH 15, 2011 | |
8:45–9:15 am | Continental breakfast |
9:15–9:30 am | Summary of Day One and Preview of Day Two: David Relman, M.D., Chair, Forum on Microbial Threats |
SESSION 3: Using Synthetic/Systems Biology Approaches to Manage Biofilms | |
9:30–10:00 am | Harnessing and controlling social activities of bacteria E. Peter Greenberg, Ph.D., University of Washington |
10:00–10:30 am | Developing a synthetic biology device that detects biofilm formation on indwelling catheters Paul Freemont, Prof., Imperial College London |
10:30–10:45 am | Break |
10:45–11:15am | Novel approaches to combat biofilm drug tolerance Kim Lewis, Ph.D., Northeastern University |
11:15–11:45 am | Engineering viruses to destroy biofilms Timothy Lu, M.D., Ph.D., Massachusetts Institute of Technology |
11:45–12:15 pm | Discussion |
12:15–1:00 pm | Lunch |
SESSION 4: Synthetic/Systems Biology Products and Platforms: Potential for Novel Preventives, Diagnostics, and Therapeutics in Infectious Diseases | |
1:00–1:30 pm | Engineering microbial metabolism for production of antimalarial drugs Jay Keasling, Ph.D., University of California, Berkeley |
1:30–2:00 pm | Dynamics of clonal evolution: Immune system on a chip Jim Heath, Ph.D., California Institute of Technology |
2:00–2:30 pm | Using systems biology to understand and develop more effective vaccines Bali Pulendran, Ph.D., Emory University |
2:30–2:45 pm | Break |
2:45–3:15 pm | HTP screening system based on synthetic genes and proteins Stephen Johnston, Ph.D., Arizona State University |
3:15–3:45 pm | Synthetic biology and the art of biosensor design Chris French, Ph.D., University of Edinburgh |
3:45–4:45 pm | Open Discussion with Panelists, Forum Members, and Audience |
4:45–5:00 pm | Wrap-up Discussion, Jim Hughes and David Relman |
5:00 pm | Meeting Adjourns |
