| 4-D | four dimension (time as the 4th dimension) |
| AAS | Advanced Automation System |
| ADS-B | Automatic Dependent Surveillance-Broadcast |
| ADS-R | Automatic Dependent Surveillance-Rebroadcast |
| AMS | acquisition management system |
| ASSC | Airport Surface Surveillance Capability |
| ATC | air traffic control |
| CMMI | capability maturity model integration |
| CONOPS | concept of operations |
| DoDAF | Department of Defense Architecture Framework |
| DOT | Department of Transportation |
| EGPWS | enhanced ground proximity warning system |
| ERAM | En Route Automation Modernization |
| FAA | Federal Aviation Administration |
| FAR | Federal Acquisition Regulation |
| FDM | Flight Data Manager |
| FIS-B | Flight Information Service–Broadcast |
| GA | general aviation |
| GAO | Government Accountability Office |
| GPS | Global Positioning System |
| HITLS | human-in-the-loop simulations |
| HSI | human service interaction |
| IEEE | Institute of Electrical and Electronics Engineers |
| ISEF | integrated systems engineering framework |
| IT | information technology |
| JPDO | Joint Planning and Development Office |
| MSAW | minimum safe altitude warning |
| NAS | National Airspace System |
| NAS ISEF | National Airspace System integrated systems engineering framework |
| NextGen | Next Generation Air Transportation System |
| NIST | National Institute of Standards and Technology |
| NRC | National Research Council |
| OMB | Office of Management and Budget |
| PBN | performance-based navigation |
| Pre-RFP | pre-request for proposal |
| RF | radio frequency |
| RNAV | area navigation |
| RNP | required navigation performance |
| SBS | Surveillance and Broadcast Services |
| STARS/TAMR | Standard Terminal Automation Replacement System/Terminal Automation Modernization and Replacement |
| SWIM | System Wide Information Management |
| TCAS | traffic collision avoidance system |
| TIS-B | Traffic Information Service-Broadcast |
| TSA | Transportation Security Administration |
| UAS | unmanned aircraft system |
| UX | user experience design |
| VHF | very high frequency |
| WAAS | wide area augmentation system |
| WAM | Wide Area Multilateration |
| ZLA ARTCC | Los Angeles En-Route Air Traffic Control Center |
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