Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop (2017)

Chapter: 5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies

Previous Chapter: 4 Regulatory and Reimbursement Considerations
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

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Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

There was a problem loading page 45.

Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.

There was a problem loading page 46.

Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 37
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 38
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 39
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 40
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 41
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 42
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 43
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 44
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 45
Suggested Citation: "5 Trial Designs to Establish Efficacy and Safety in Multimodal Therapies." National Academies of Sciences, Engineering, and Medicine. 2017. Developing Multimodal Therapies for Brain Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/23657.
Page 46
Next Chapter: 6 Developing Multimodal Therapies: Practical Considerations Relating to Industry
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