Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop (2017)

Chapter: 2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities

Previous Chapter: 1 Introduction and Overview
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

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Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

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Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

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Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 8.

Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 9.

Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

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Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 11.

Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 12.

Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 13.

Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 14.

Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 5
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 6
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 7
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 8
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 9
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 10
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 11
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 12
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 13
Suggested Citation: "2 Drug Development for Nervous System Disorders: Overview of Challenges and Potential Opportunities." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
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Next Chapter: 3 Case Studies: Therapeutic Development for Parkinson's Disease and Schizophrenia in the Absence of Predictive Animal Models of Disease
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