Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop (2017)

Chapter: 5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials

Previous Chapter: 4 New Modeling Approaches for Nervous System Disorders
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

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Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 34.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 35.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 36.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 37.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 38.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 39.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 40.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 41.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 42.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 43.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.

There was a problem loading page 44.

Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 33
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 34
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 35
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 36
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 37
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 38
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 39
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 40
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 41
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 42
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
Page 43
Suggested Citation: "5 Private-Sector Thresholds for Investment in Neuroscience Clinical Trials." National Academies of Sciences, Engineering, and Medicine. 2017. Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/24672.
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Next Chapter: 6 Ethical Considerations
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