| ACR | acute-to-chronic ratio |
| ADIOS2 | Automated Data Inquiry for Oil Spills version 2 |
| API | American Petroleum Institute |
| BaPE | benzo[a]pyrene equivalents |
| BOP | blowout preventer |
| BSEE | Bureau of Safety and Environmental Enforcement |
| BTEX | benzene, toluene, ethylbenzene, and xylene |
| BW | body weight |
| CAFE | Chemical Aquatic Fate and Effects |
| CDC | Centers for Disease Control and Prevention |
| CERA | Consensus Ecological Risk Assessment |
| CEWAF | chemically enhanced water-accommodated fraction |
| CF | conversion factor |
| CI | confidence interval |
| CR | consumption rate |
| CRA | Comparative Risk Assessment |
| CROSERF | Chemical Response to Oil Spills: Ecological Effects Research Forum |
| CSF | cancer slope factor |
| DFO | Fisheries and Oceans Canada (Department of Fisheries and Oceans) |
| DIVER | Data Integration Visualization Exploration and Reporting |
| DOR | dispersant-to-oil ratio |
| DOSS | dioctyl sodium sulfosuccinate |
| DS | model proposed by Delvigne & Sweeney or DeepSpill |
| DSD | droplet size distribution |
| DWH | Deepwater Horizon |
| ED | exposure duration |
| EIS | Environmental Impact Statement |
| EL50 | median effects-loading concentration |
| EPA | U.S. Environmental Protection Agency |
| EPS | extracellular polymeric substance |
| EqP | equilibrium partitioning |
| ERL | effects range low |
| ES | ecosystem services |
| ESA | ecosystem services analysis |
| FDA | U.S. Food and Drug Administration |
| FEV | forced expiratory volume |
| FVC | forced vital capacity |
| GC | gas chromatography |
| GC-FID | gas chromatography and flame ionization detection |
| GC-MS | gas chromatography and mass spectrometry |
| GDS | Global Dispersant Stockpile |
| GNOME | General NOAA (National Oceanic and Atmospheric Administration) Operational Modeling Environment |
| GoMRI | Gulf of Mexico Research Initiative |
| GOR | gas-to-oil ratio |
| GRIIDC | Gulf of Mexico Research Initiative Information & Data Cooperative |
| HC5 | hazard concentration 5% |
| HEWAF | high-energy water-accommodated fraction |
| HYCOM | Hybrid Coordinate Ocean Model |
| IDLH | Immediately Dangerous to Life or Health |
| IFT | interfacial tension |
| IOGP | International Association of Oil & Gas Producers |
| IRB | Institutional Review Board |
| ISB | in situ burning |
| IVOC | intermediate-volatility organic compound |
| LC50 | median lethal concentration |
| LEWAF | low energy water-accommodated fraction |
| LISST | Laser In Situ Scattering and Transmissiometry |
| LL50 | lethal loading 50 |
| LN | log-normal |
| LOC | level of concern |
| LT50 | lethal time 50 |
| MAH | monoaromatic hydrocarbon |
| MD | microdroplet concentration |
| MEWAF | medium-energy water-accommodated fraction |
| MEXUS | Mexico–United States |
| MOS | marine oil snow |
| MOSSFA | Marine Oil Snow Sedimentation and Flocculent Accumulation |
| MPa | megapascal |
| MS | mass spectrometry |
| NAPL | non-aqueous-phase liquid |
| NEBA | Net Environmental Benefit Analysis |
| NIEHS | National Institute of Environmental Health Sciences |
| NIOSH | National Institute for Occupational Safety and Health |
| NMFS | National Marine Fisheries Service |
| NOAA | National Oceanic and Atmospheric Administration |
| NRC | National Research Council |
| NRDA | Natural Resource Damage Assessment |
| NRT | National Response Team |
| OMA | oil-mineral aggregate |
| OPA | oil-particle aggregate |
| ORMS | oil-related marine snow |
| OSHA | Occupational Safety and Health Administration |
| PAH | polycyclic aromatic hydrocarbon |
| PDMS | polydimethylsiloxane |
| PLC50 | median phototoxic lethal concentration |
| PPE | personal protective equipment |
| PTSD | posttraumatic stress disorder |
| RANS | Reynolds-Averaged Navier-Stokes |
| RfD | reference dose |
| RL | risk level |
| ROC | resource of concern |
| SABGOM | South Atlantic Bight—Gulf of Mexico |
| SilCam | silhouette camera |
| SIMA | Spill Impact Mitigation Assessment |
| SOA | secondary organic aerosol |
| SOO | spill of opportunity |
| SPME | solid-phase microextraction |
| SSD | Species Sensitivity Distribution |
| SSDI | subsea dispersant injection |
| SVOC | semi-volatile organic compound |
| SwRI | Southwest Research Institute |
| TAMOC | Texas A&M Oilspill Calculator |
| THC | total hydrocarbon concentration |
| TLM | target lipid model |
| TPAH | total polycyclic aromatic hydrocarbon |
| TPH | total petroleum hydrocarbon |
| TROPICS | Tropical Oil Pollution Investigations in Coastal Systems |
| TU | toxic unit |
| TUHH | Hamburg University of Technology |
| UI | uncertainty interval |
| UNCLOS | United Nations Convention on the Law of the Sea |
| USCG | U.S. Coast Guard |
| UV | ultraviolet |
| VEC | valued ecosystem component |
| VOC | volatile organic compound |
| WAF | water-accommodated fraction |