Next Steps for Functional Genomics: A Workshop
February 10–12, 2020
National Academy of Sciences, Room 120
2101 Constitution Avenue, NW, Washington, DC 20418
| 8:45 | Welcome and Opening Remarks |
| Steven Moss, National Academies of Sciences, Engineering, and Medicine | |
| Donal Manahan, National Science Foundation | |
| Gene Robinson, University of Illinois at Urbana-Champaign, Chair of the Steering Committee | |
| 9:00 | Keynote Speaker |
| Introduced by Gene Robinson, University of Illinois at Urbana-Champaign | |
| Design for Inference in Biology | |
| Aviv Regev, Broad Institute and Massachusetts Institute of Technology | |
| 10:00–10:15 | Coffee Break |
| 10:15 | Talks and Facilitated Panel Discussion: Case Studies on Building Functional Genomics Tools in Diverse Systems |
| 15-minute talks from each person followed by panel guided questions and discussion | |
| Moderator: Lauren O’Connell, Stanford University | |
| Andrea Sweigart, University of Georgia | |
| Rachel Dutton, University of California, San Diego | |
| Zoe Donaldson, University of Colorado Boulder | |
| Dominique Bergmann, Stanford University | |
| Steven Henikoff, Fred Hutchinson Cancer Research Center | |
| 12:00–1:00 | Lunch |
| 1:00 | Facilitated Panel Discussion: Determining and Defining “Model” Systems for Diverse Functional Genomics Applications |
| 10-minute introduction to topic from Paul Katz followed by a facilitated discussion | |
| Moderator: Andrea Sweigart, University of Georgia | |
| Paul Katz, University of Massachusetts Amherst | |
| Lauren O’Connell, Stanford University | |
| Zoe Donaldson, University of Colorado Boulder | |
| Dominique Bergmann, Stanford University | |
| 2:15 | Talks and Facilitated Panel Discussion: Understanding the Contributions of the Non-Protein-Coding DNA to Phenotype |
| 15-minute talks from each person followed by panel-guided questions and discussion | |
| Moderator: Terry Magnuson, University of North Carolina at Chapel Hill | |
| Felicity Jones, Friedrich Miescher Laboratory of the Max Planck Society | |
| Scott Edwards, Harvard University | |
| Francois Spitz, The University of Chicago | |
| 3:45–4:00 | Coffee/Snack Break |
| 4:00 | Facilitated Panel Discussion: Societal and Ethical Implications of Functional Genomics Research |
| 5 minutes of opening comments by each panelist, followed by a facilitated discussion | |
| Moderator: Zoe Donaldson, University of Colorado Boulder | |
| Rebecca Walker, University of North Carolina at Chapel Hill | |
| Scott Jackson, Bayer Crop Science | |
| Ronald Sandler, Northeastern University | |
| 5:00 | Closing Remarks |
| Philip Benfey, Duke University | |
| 5:00 | Adjourn |
| 9:00 | Keynote Speaker |
| Introduced by Trudy Mackay, Clemson University | |
| Predicting Current and Future Sources of Variation in Quantitative Traits | |
| Patricia Wittkopp, University of Michigan | |
| 10:00–10:15 | Coffee Break |
| 10:15 | Talks and Facilitated Panel Discussion: Advancement of Research on Environmental Regulation of Gene Function |
| 15-minute talks from each person followed by panel-guided questions and discussion | |
| Moderator: Philip Benfey, Duke University | |
| Sarah Kocher, Princeton University | |
| Joanna Kelley, Washington State University | |
| Nathan Springer, University of Minnesota | |
| Trudy Mackay, Clemson University | |
| 12:00–1:00 | Lunch |
| 1:00 | Talks and Facilitated Panel Discussion: Challenges and Successes of Integrating Large Datasets |
| 15-minute talks from each person followed by panel-guided questions and discussion | |
| Moderator: Norbert Tavares, Chan Zuckerberg Initiative | |
| Alexis Battle, Johns Hopkins University | |
| Saurabh Sinha, University of Illinois at Urbana-Champaign | |
| Rahul Satija, New York Genome Center | |
| Charles Danko, Cornell University | |
| Genevieve Haliburton, Chan Zuckerberg Initiative |
| 2:20 | Facilitated Panel Discussion: Pros and Cons of Consortia and Large Databases |
| 2–3 minutes of opening comments by each panelist, followed by a facilitated discussion | |
| Moderator: Charles Danko, Cornell University | |
| Felicity Jones, Friedrich Miescher Laboratory of the Max Planck Society | |
| Alexis Battle, Johns Hopkins University | |
| Saurabh Sinha, University of Illinois at Urbana-Champaign | |
| Rahul Satija, New York Genome Center | |
| Sean Hanlon, National Cancer Institute, National Institutes of Health | |
| 3:15–3:30 | Coffee/Snack Break |
| 3:30 | Interactive Session and Panel Discussion: Addressing Challenges in Education and Training |
| Groups of 6–8 will discuss prompt questions from 3:15–3:45. Each group will have 3–5 minutes to summarize its main points. We will then move into a panel discussion. | |
| Moderator: Patricia Wittkopp, University of Michigan | |
| Terry Magnuson, University of North Carolina at Chapel Hill | |
| Arnaud Martin, The George Washington University | |
| Lauren O’Connell, Stanford University | |
| Grace Anderson, Octant | |
| Rebecca Walker, University of North Carolina at Chapel Hill | |
| 5:00 | Closing Remarks |
| Emma Farley, University of California, San Diego | |
| 5:05 | Adjourn |
| 9:00 | Talks and Facilitated Panel Discussion: Interpreting and Validating Results from High-Throughput Screening Approaches |
| 15-minute talks from each person followed by panel-guided questions and discussion |
| Moderator: Trudy Mackay, Clemson University | |
| David C. Page, Whitehead Institute | |
| Emma Farley, University of California, San Diego | |
| Philip Benfey, Duke University | |
| Grace Anderson, Octant | |
| Gary Churchill, The Jackson Laboratory | |
| 10:45 | Interactive Session on the Future of Functional Genomics Research Goals |
| Participants will get into groups of 6–8 to think about the prompt questions related to short- and medium-term research goals of functional genomics. These groups will discuss from 10:40–11:20, followed by 5 minutes of reporting from each group on the main points it came up with. This will end with a larger discussion by all attendees. | |
| Moderator: Emma Farley, University of California, San Diego | |
| 11:45 | Future of Functional Genomics Town Hall |
| This is a final opportunity for any attendee to emphasize a point they heard during the meeting or bring up something that has not been addressed. Possible prompt questions will be provided. | |
| Moderator: Gene Robinson, University of Illinois at Urbana-Champaign, Chair of the Steering Committee | |
| 12:25 | Closing Remarks |
| Gene Robinson, University of Illinois at Urbana-Champaign, Chair of the Steering Committee | |
| 12:30 | Meeting Adjourn |
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