Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations (2020)

Chapter: Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee

Previous Chapter: Appendix B: National Academies Reports Related to Gulf Theater Veterans' Health
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.

Appendix C

Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed
*by the Committee

ReferenceaPopulation1990–1991 Gulf WarPost-9/11Study PopulationbOutcomes AssessedcSmoking Status Collectedd
Abraham and Baird, 2012U.S. active-duty service membersXAsthma;
COPD;
Pneumonia
Abraham et al., 2012U.S. service membersXRespiratory Symptoms (ICD-9-CM 786);
Asthma;
COPD;
Chronic Bronchitis
Abraham et al., 2014U.S. service membersXAFHSCRespiratory Symptoms (ICD-9-CM 786);
Asthma;
COPD
Baird et al., 2012U.S./active-duty Army personnelXRespiratory Symptoms (ICD-9-CM 786);
Sinusitis and Rhinitis;
Asthma;
COPD;
Acute Bronchitis (ICD-9CM 460–466)
Banoei et al., 2019U.S. veteransXXInterstitial Lung Disease (sarcoidosis)
Barth et al., 2014U.S. veteransXNewGenSinusitis and Rhinitis;
Asthma;
Chronic Bronchitis
X
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
ReferenceaPopulation1990–1991 Gulf WarPost-9/11Study PopulationbOutcomes AssessedcSmoking Status Collectedd
Barth et al., 2016aU.S. veteransXNewGenSinusitis and Rhinitis;
Asthma;
Chronic Bronchitis
X
Barth et al., 2016bU.S. veteransXMortality
Bollinger et al., 2015U.S. veteransXMortality
Butzko et al., 2019U.S. veteransXWRIISCPulmonary Function TestingX
Davy et al., 2012Australian Defence Force active-duty personnelXPulmonary Function Testing;
COPD
X
DelVecchio et al., 2015U.S. active-duty Army personnelXAsthma
Díaz Santana et al., 2017U.S. veteransXNewGenSleep Apnea
Dion et al., 2013U.S. Army soldiersXVocal Cord DysfunctionX
Eick et al., 2011U.S. active-duty service membersXPneumonia
Falvo et al., 2016aU.S. veteransXWRIISCPulmonary Function TestingX
Falvo et al., 2016bU.S. veteransXWRIISCPulmonary Function Testing
Forbes et al., 2019U.S. active-duty service membersXInterstitial Lung Disease (sarcoidosis)
Gwini et al., 2016Australian veteransXSleep Apnea;
Asthma
X
Hines et al., 2013U.S. veteransXVA Depleted Uranium Surveillance ProgramRespiratory Symptoms (frequent cough, coughing up phlegm, shortness of breath, wheezing);
Sinusitis and Rhinitis;
Pulmonary Function Testing;
Asthma;
Emphysema
X
Holley et al., 2016U.S. service members, National Guard/reservesXPulmonary Function TestingX
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
ReferenceaPopulation1990–1991 Gulf WarPost-9/11Study PopulationbOutcomes AssessedcSmoking Status Collectedd
Hooper et al., 2008U.S. active-duty veterans of Gulf WarXSinusitis and Rhinitis;
Interstitial Lung Disease (sarcoidosis);
Pneumonia
Jani et al., 2017aU.S. service membersXAH&OBP Registry/WRIISCRespiratory Symptoms (dyspnea, decreased exercise tolerance)X
Jani et al., 2017bU.S. service membersXAH&OBP RegistryConstrictive BronchiolitisX
Khalil et al., 2018U.S. veteransXGulf War Era Cohort and BiorepositoryRespiratory Symptoms (difficulty breathing, shortness of breath, frequent coughing without a cold, wheezing in chest);
Sleep Apnea;
COPD;
Emphysema;
Constrictive Bronchiolitis;
TB;
Cancers
King et al., 2011U.S. active-duty Army soldiersXConstrictive BronchiolitisX
Krefft et al., 2017U.S. veteransXRespiratory Symptoms (cough, chest tightness, wheezing, shortness of breath, decreased exercise tolerance);
Pulmonary Function Testing;
Emphysema;
Constrictive Bronchiolitis;
Interstitial Lung Disease (hypersensitivity pneumonitis)
X
Krefft et al., 2020U.S. service membersXPulmonary Function Testing;
Emphysema;
Constrictive Bronchiolitis;
Interstitial Lung Disease (hypersensitivity pneumonitis)
X
Lindheimer et al., 2019U.S. veteransXWRIISCPulmonary Function TestingX
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
ReferenceaPopulation1990–1991 Gulf WarPost-9/11Study PopulationbOutcomes AssessedcSmoking Status Collectedd
Liu et al., 2016U.S. service membersXAH&OBP RegistryAsthma;
COPD;
Emphysema;
Chronic Bronchitis
X
Madar et al., 2017U.S. military personnelXXPulmonary Function Testing;
Constrictive Bronchiolitis;
Interstitial Lung Disease (sarcoidosis, acute eosinophilic pneumonia, pulmonary alveolar proteinosis, idiopathic interstitial pneumonia)
X
Matthews et al., 2014U.S. active-duty service membersXPulmonary Function Testing;
COPD;
Emphysema
X
Maule et al., 2018Veterans (Australia, Denmark, United Kingdom, United States)XRespiratory Symptoms (coughing, wheezing, shortness of breath);
Sinusitis and Rhinitis;
Asthma
Morris et al., 2014U.S. active-duty service membersXSTAMPEDERespiratory Symptoms (dyspnea, cough, wheeze, sputum production);
Pulmonary Function Testing
Morris et al., 2019U.S. active-duty Army personnelXSTAMPEDERespiratory Symptoms (dyspnea, cough, wheezing, sputum production, exercise intolerance);
Pulmonary Function Testing
X
Morris et al., 2020U.S. service membersXSTAMPEDERespiratory Symptoms (exertional dyspnea, cough, wheeze, sputum production, decreased exercise tolerance);
Pulmonary Function Testing;
Constrictive Bronchiolitis
X
OIF SAPEG, 2003U.S. active duty military personnel, Reserve/National GuardXInterstitial Lung Disease (acute eosinophilic pneumonia)X
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
ReferenceaPopulation1990–1991 Gulf WarPost-9/11Study PopulationbOutcomes AssessedcSmoking Status Collectedd
Peacock et al., 1997U.S. veteransXComprehensive Clinical Evaluation ProgramSleep Apnea
Pugh et al., 2016U.S. veteransXAsthma;
COPD;
Interstitial Lung Disease
X
Rivera et al., 2018U.S. service members, Reserve/National GuardXMillennium Cohort StudyAsthmaX
Rohrbeck et al., 2016U.S. active-duty service membersXRespiratory Symptoms (ICD-9-CM 786);
Sleep Apnea;
Cancers
Roop et al., 2007U.S. active-duty Army soldiersXAsthmaX
Saers et al., 2017Swedish military personnelXRespiratory Symptoms (wheeze, wheeze with breathlessness, wheeze without a cold, nocturnal chest tightness, nocturnal breathlessness, nocturnal cough);
Chronic Bronchitis
X
Sharkey et al., 2015U.S. service membersXAFHSCRespiratory Symptoms (ICD-9-CM 786);
Asthma;
COPD;
Acute Bronchitis
X
Sharkey et al., 2016U.S. service membersXAFHSCRespiratory Symptoms (ICD-9-CM 786);
Asthma;
COPD
X
Shorr et al., 2004U.S. active-duty service membersXInterstitial Lung Disease (acute eosinophilic pneumonia)X
Sine et al., 2018U.S. active-duty service membersXInterstitial Lung Disease (acute eosinophilic pneumonia)X
Smith et al., 2008U.S. active-duty service membersXMillennium Cohort StudySinusitis and Rhinitis;
Sleep Apnea;
Asthma;
Emphysema;
Chronic Bronchitis
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
ReferenceaPopulation1990–1991 Gulf WarPost-9/11Study PopulationbOutcomes AssessedcSmoking Status Collectedd
Smith et al., 2009U.S. service members, Reserve/National GuardXMillennium Cohort StudyRespiratory Symptoms (persistent or recurring cough or shortness of breath);
Asthma;
Emphysema;
Chronic Bronchitis
X
Smith et al., 2012U.S. service membersXMillennium Cohort StudyRespiratory Symptoms (persistent or recurring cough or shortness of breath);
Asthma;
Emphysema;
Chronic Bronchitis
X
Soltis et al., 2009U.S. active-duty service membersXAcute Bronchitis
Szema et al., 2010U.S. veteransXAsthma
Szema et al., 2011U.S. veteransXPulmonary Function TestingX
Taylor and Ross, 2019British active-duty service personnelXRespiratory Symptoms (shortness of breath, wheeze, cough);
Sinusitis and Rhinitis
Weinstein et al., 2016U.S. active-duty service membersXPulmonary Function Testing
Woods et al., 2018U.S. active-duty Army personnelAsthmaX
Zundel et al., 2019U.S. veteransXAsthma;
Chronic Bronchitis
X

* “Newly Reviewed” studies are those that have not been addressed in previous National Academies reports.

a Full citations may be found in the References section of Chapter 4.

b Study populations of cohorts that were specified in the Statement of Task are noted.

c Only those outcomes that are addressed in the report are listed. A study may have also addressed other outcomes.

d An “X” indicates that information on smoking was collected, but this does not necessarily mean that it was collected consistently or used in analyses.

NOTE: AFHSC, Armed Forces Health Surveillance Center; AH&OBP, Airborne Hazards and Open Burn Pit; COPD, chronic obstructive pulmonary disease; ICD-9-CM, International Classification of Diseases, 9th edition, Clinical Modification; NewGen, National Health Study for a New Generation of U.S. Veterans; STAMPEDE, Study of Active Duty Military for Pulmonary Disease Related to Environmental Deployment Exposures; TB, tuberculosis; WRIISC, VA War Related Illness and Injury Study Center.

Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
Page 243
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
Page 244
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
Page 245
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
Page 246
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
Page 247
Suggested Citation: "Appendix C: Epidemiologic Studies of Respiratory Health Outcomes in Southwest Asia Theater Veterans Newly Reviewed* by the Committee." National Academies of Sciences, Engineering, and Medicine. 2020. Respiratory Health Effects of Airborne Hazards Exposures in the Southwest Asia Theater of Military Operations. Washington, DC: The National Academies Press. doi: 10.17226/25837.
Page 248
Next Chapter: Appendix D: Committee Member and Staff Biographical Sketches
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