| A2/AD | anti-access/area denial |
| AADC | Area Air Defense Commander |
| ABMS | Advanced Battle Management System |
| ACA | airspace control authority |
| ACC | Air Combat Command |
| ADSV | ABMS DeviceONE SecureView |
| AFC | Army Futures Command |
| AFMC | Air Force Materiel Command |
| AFRL | Air Force Research Laboratory |
| AFSC | Air Force Specialty Code |
| AI | artificial intelligence |
| AOC | Air Operations Center |
| AOC-WS | Air Operations Center—Weapon System |
| API | Application Program Interface |
| ARB | architecture review board |
| ATO | Air Tasking Order |
| AutoML | automated machine learning |
| AWACS | Airborne Warning and Control System |
| BPM | business process management |
| C2 | command and control |
| C3I | command, control, communications, and intelligence |
| C4ISR | command, control, communications, computers, intelligence, surveillance, reconnaissance |
| CACE | changing anything changes everything |
| CAO | Chief Architect’s Office |
| CCSDS | Consultative Committee for Space Data Systems |
| CFT | cross functional team |
| CI/CD | continuous integration/continuous delivery |
| CIO | Chief Information Officer |
| CMCC | Common Mission Control Center |
| COP | common operating picture |
| CR1 | capability release one |
| CR2 | capability release two |
| CSO | Chief Software Officer |
| CSTE | common simulation training environment |
| DAF | Department of the Air Force |
| DAF RCO | Department of the Air Force Rapid Capabilities Office |
| DARPA | Defense Advanced Research Projects Agency |
| DAU | Defense Acquisition University |
| DDR&E | U.S. Department of Defense Research and Engineering Enterprise |
| DE | digital engineering |
| DevSecOps | development, security, and operations |
| DFARS | Defense Federal Acquisition Regulation Supplement |
| DISA | Defense Information Systems Agency |
| DoD | U.S. Department of Defense |
| DoN | Department of the Navy |
| DOTMLPF-P | doctrine, organization, training, materiel, leadership, education, personnel, facilities, and policy |
| DSOP | U.S. Department of Defense Enterprise DevSecOps Initiative |
| DTO | Digital Transformation Office |
| EW | electronic warfare |
| FFTTEA | find, fix, target, track, engage, and assess |
| FNC3 | fully networked command, control, and communications |
| FOS | family of systems |
| FY | fiscal year |
| GAO | Government Accountability Office |
| GBSD | ground-based strategic deterrent |
| GPS | global positioning system |
| HCI | human-computer interface |
| HFE | human factors engineering |
| HQ | headquarters |
| HQE | highly qualified expert |
| HSI | human system integration |
| HUD | heads-up display |
| iBPMS | intelligent business process management suites |
| ICAM | identity, credential, and access management |
| IEEE | Institute of Electrical and Electronics Engineers |
| IO | information operations |
| IoT | Internet of Things |
| IP | intellectual property |
| iPaaS | integration platform as a service |
| ISR | intelligence, surveillance, reconnaissance |
| IT | information technology |
| JADC2 | Joint All-Domain Command and Control |
| JAPCC | Joint Air Power Competence Centre |
| JFACC | Joint Forces Air Component Commander |
| JFC | Joint Force Commander |
| JROC | Joint Requirements Oversight Council |
| JSTARS | Joint Surveillance and Target Attack Radar System |
| JWC | Joint Warfighting Concept |
| KREL | Kessel Run Experimentation Lab |
| LOE | line of effort |
| M&S | modeling and simulation |
| MBSE | model-based systems engineering |
| MFA | multi-factor authentication |
| ML | machine learning |
| MLS | multi-level security |
| MOSA | modular open systems architecture |
| NATO | North Atlantic Treaty Organization |
| NC3 | nuclear command, control, communications |
| NDS | National Defense Strategy |
| NGAD | next generation air dominance |
| NORAD | North American Aerospace Defense Command |
| NSCAI | National Security Commission on Artificial Intelligence |
| OMG | Object Management Group |
| OODA | observe-orient-decide-act |
| OPR | office of primary responsibility |
| OSA | open system architecture |
| OSD | Office of the Secretary of Defense |
| OUSD A&S | Office of the Under Secretary of Defense for Acquisition and Sustainment |
| PATS | protected anti-jam tactical satellite communications |
| PC | Project Convergence |
| PEO | program executive office |
| PRC | People’s Republic of China |
| R&D | research and development |
| RDA | research, development, acquisition |
| RPA | robotic process automation |
| SAE | Service Acquisition Executive |
| SAF/AQ | Assistant Secretary of the Air Force for Acquisition, Technology, and Logistics |
| SATCOM | satellite communication |
| SCARS | simulator common architectures requirements and standards |
| SEP | systems engineering process |
| shOC-N | Shadow Operations Center-Nellis |
| SIPRNET | secret Internet protocol router network |
| SOCOM | Special Operations Command |
| SOF | Special Operations Forces |
| SOFIC | Special Operations Forces industry conference |
| SOH | safety and occupational health |
| STITCHES | system of systems technology integration tool chain for heterogeneous electronic systems |
| T&E | testing and evaluation |
| TMD | theater missile defense |
| TTA | time-triggered architecture |
| TTP | tactics, techniques, and procedures |
| UCI | universal command and control interface |
| UDL | Unified Data Library |
| USCYBERCOM | U.S. Cyber Command |
| USN | U.S. Navy |
| USNORTHCOM | U.S. Northern Command |
| USSF | U.S. Space Force |
| USSPACECOM | U.S. Space Command |
| USSTRATCOM | U.S. Strategic Command |
| VV&A | verification, validation, and accreditation |
| W1 | WeaponONE |
| ZT | zero trust |