Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop (2025)

Chapter: Appendix B: Workshop Agenda

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Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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Appendix B

Workshop Agenda

OCTOBER 28, 2024

8:30 am Welcome and Opening Remarks
Planning Committee Co-Chairs:
  • Beth Karlan, University of California, Los Angeles
  • Lawrence Shulman, University of Pennsylvania
9:00 am Session 1: Overview of Multicancer Detection Testing
Co-Moderators:
  • Beth Karlan, University of California, Los Angeles
  • Lawrence Shulman, University of Pennsylvania
Keynote Presentation: How Much Do You Want to Know? The Peril and Promise of an MCD-Driven Future
  • W. Kimryn Rathmell, National Cancer Institute; presented by Philip Castle, National Cancer Institute
History of Cancer Early Detection Studies
  • Robert Smith, American Cancer Society
How Multicancer Detection Testing Works
  • William Grady, Fred Hutchinson Cancer Center
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Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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Panel Discussion
Session speakers and
  • Cheryl Ivey Green, First Baptist Church of South Richmond
  • Jody Hoyos, Prevent Cancer Foundation
  • Sue Friedman, FORCE: Facing Our Risk of Cancer Empowered (Virtual)
  • Christos Patriotis, National Cancer Institute
10:45 am Break
11:00 am Session 2: MCD Test Validation
Co-Moderators:
  • Ruth Etzioni, Fred Hutchinson Cancer Center
  • Beth Karlan, University of California, Los Angeles
Diagnostic Performance: The Many Faces of Screening Test Sensitivity
  • Ruth Etzioni, Fred Hutchinson Cancer Center
Clinical Trials for Evaluating the Mortality Benefits of MCD Testing
  • Hormuzd Katki, National Cancer Institute
Alternative Endpoints for MCD Clinical Trials
  • Hilary Robbins, International Agency for Research on Cancer (Virtual)
Addressing the Gap between Performance and Outcomes in the Absence of MCD Randomized Trials
  • Jane Lange, Cancer Early Detection Advanced Research Center, Oregon Health and Science University
Panel Discussion
Session speakers and
  • Philip Castle, National Cancer Institute
12:30 pm Break
1:30 pm Session 3: Examples of MCD Tests in Development and Clinical Use
Co-Moderators:
  • Philip Castle, National Cancer Institute
  • Lawrence Shulman, University of Pennsylvania
Page 47 Cite Bookmark
Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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Overview of MCD Tests in Development and Clinical Practice
  • Wendy Rubinstein, National Cancer Institute
Discussion of Evidence: Industry Perspective
Session speakers and
  • Tomasz M. Beer, Exact Sciences
  • Craig Eagle, Guardant Health
  • Eric Klein, GRAIL
2:50 pm Break
3:05 pm Session 4: Strategies for Implementing MCD Tests into Clinical Practice
Co-Moderators:
  • Elena Martínez, University of California, San Diego
  • Chanita Hughes-Halbert, University of Southern California
Primary Care Perspective
  • Richard Hoffman, University of Iowa
Radiology Perspective
  • Stella Kang, New York University Langone Health
Oncology Care Perspective
  • Deborah Schrag, Memorial Sloan Kettering Cancer Center
Health Care Delivery System Perspective
  • Nancy Keating, Harvard Medical School and Brigham and Women’s Hospital
Implementation Sciences Perspective
  • Ora Gordon, Saint John’s Cancer Institute and Providence Health
Guideline Development Perspective
  • Alex Krist, Virginia Commonwealth University
Panel Discussion
Session speakers and
  • Ronald Myers, Thomas Jefferson University
  • Chyke Doubeni, The Ohio State University
5:00 pm Adjourn Day 1
Page 48 Cite Bookmark
Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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OCTOBER 29, 2024

8:30 am Session 5: Health System and Policy Considerations
Co-Moderators:
  • Etta Pisano, American College of Radiology
  • Robert Winn, Massey Comprehensive Cancer Center, Virginia Commonwealth University
Health Equity Considerations with MCD Testing
  • Carmen Guerra, Penn Medicine, University of Pennsylvania
  • Rachel Issaka, Fred Hutchinson Cancer Center
Health Economic Considerations
  • Ya-Chen Tina Shih, University of California, Los Angeles
  • Scott Ramsey, Fred Hutchinson Cancer Center
Health Insurance and Coverage Considerations
  • Jill Hagenkord, Optum Genomics
  • Kathryn A. Phillips, University of California, San Francisco
Panel Discussion
10:00 am Break
10:15 am Session 6: Wrap Up Discussion
Co-Moderators:
  • Beth Karlan, University of California, Los Angeles
  • Lawrence Shulman, University of Pennsylvania
Panelists:
  • Session 1: Beth Karlan and Lawrence Shulman
  • Session 2: Ruth Etzioni (Virtual) and Beth Karlan
  • Session 3: Lawrence Shulman
  • Session 4: Elena Martínez and Chanita Hughes-Halbert
  • Session 5: Etta Pisano and Robert Winn
11:30 am Adjourn
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Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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Page 46 Cite Bookmark
Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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Page 47 Cite Bookmark
Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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Page 48 Cite Bookmark
Suggested Citation: "Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Opportunities and Challenges for the Development and Adoption of Multicancer Detection Tests: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/29114.
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