Diagnostic Tools, Gaps, and Collaborative Pathways in Human H5N1 Detection: Rapid Expert Consultation
2025

Rapid_expert_consultation

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Diagnostics are the first line of defense to infectious disease outbreaks. The rapid spread of Influenza A (H5N1) or "Bird Flu" into U.S. dairy cattle, poultry, and humans underscores the urgent need for stronger diagnostic readiness. While sustained human-to-human transmission has not yet occurred with H5N1, the risk is growing. Currently there are knowledge gaps around early case identification measures, clinical management, and coordinated public health efforts.

In response, the National Academies produced a rapid expert consultation providing a strategic and actionable analysis for strengthening domestic diagnostic capacity and infrastructure. This is the first publication of the institution's new Rapid Response to Emerging Science, Engineering, and Medicine Challenges initiative, which provides a formal platform for proactively building sustainable, crosscutting rapid response capabilities.

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Overview of the Rapid Expert Consultation

Publication information

36 pages · 8.5 x 11 ·
ISBN Ebook: 0-309-60052-9
DOI: https://doi.org/10.17226/29273

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National Academies of Sciences, Engineering, and Medicine. 2025. Diagnostic Tools, Gaps, and Collaborative Pathways in Human H5N1 Detection: Rapid Expert Consultation. Washington, DC: The National Academies Press.

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Diagnostic Tools, Gaps, and Collaborative Pathways in Human H5N1 Detection 1-1
Executive Summary 2-3
State of Human H5N1 Diagnostics 4-27
References 28-34
Acknowledgments 35-35
Author Biosketches 36-36

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Diagnostic Tools, Gaps, and Collaborative Pathways in Human H5N1 Detection: Rapid Expert Consultation (2025)

Chapter: Executive Summary

Additional materials

Publication information

Suggested citation

My Academies

Diagnostic Tools, Gaps, and Collaborative Pathways in Human H5N1 Detection: Rapid Expert Consultation (2025)

Chapter: Executive Summary