Arsenic in Drinking Water (1999)
Chapter: Addendum to Chapter 10
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Addendum to Chapter 10
Table A10-1 Internal Cancer Data From Arsenic-exposure Studies Conducted In Taiwan Region Endemic To Blackfoot Disease
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| TABLE A10-1 Internal Cancer Data from Arsenic-Exposure Studies Conducted in Taiwan Region Endemic to Blackfoot Diseasea | |||||||||||
| No. of | Person-Years | Bladder | Liver | Lung | |||||||
| Village | Wells | Arsenic Concentration, ppm | Median | M | F | M | F | M | F | M | F |
| 3-H | 1 | 0.010 | 0.010 | 4,159 | 4,043 | 1 | 6 | 3 | 1 | 3 | 5 |
| 2-1 | 1 | 0.011 | 0.011 | 3,529 | 3,194 | 0 | 0 | 0 | 0 | 0 | 1 |
| 0-G | 5 | 0.010, 0.010, 0.030, 0.259, 0.770 | 0.030 | 5,388 | 4,861 | 3 | 2 | 3 | 3 | 4 | 5 |
| 3-5 | 1 | 0.032 | 0.032 | 7,851 | 7,033 | 3 | 3 | 5 | 2 | 6 | 2 |
| 3-N | 1 | 0.032 | 0.032 | 2,689 | 2,392 | 4 | 3 | 1 | 1 | 3 | 1 |
| 4-7 | 1 | 0.042 | 0.042 | 10,629 | 10,227 | 0 | 0 | 4 | 0 | 0 | 0 |
| 6-A | 1 | 0.045 | 0.045 | 7,716 | 6,820 | 0 | 0 | 1 | 1 | 0 | 0 |
| 0-J | 2 | 0.020, 0.080 | 0.050 | 6,501 | 5,888 | 1 | 0 | 2 | 2 | 0 | 0 |
| 3-L | 2 | 0.053, 0.058 | 0.056 | 6,238 | 5,094 | 3 | 4 | 3 | 0 | 5 | 7 |
| 4-D | 1 | 0.060 | 0.060 | 10,107 | 9,227 | 1 | 2 | 1 | 1 | 1 | 2 |
| 3-P | 1 | 0.065 | 0.065 | 6,574 | 5,927 | 0 | 0 | 3 | 0 | 2 | 5 |
| 6-C | 1 | 0.073 | 0.073 | 12,767 | 11,937 | 0 | 1 | 2 | 0 | 2 | 0 |
| 4-8 | 1 | 0.080 | 0.080 | 11,307 | 10,332 | 1 | 0 | 3 | 1 | 2 | 2 |
| 0-0 | 1 | 0.100 | 0.100 | 6,895 | 6,392 | 0 | 0 | 2 | 2 | 3 | 1 |
| O-E | 5 | 0.010, 0.085, 0.110, 0.288, 0.686 | 0.110 | 5,753 | 5,310 | 6 | 3 | 3 | 1 | 4 | 5 |
| 0-I | 7 | 0.020, 0.050, 0.110, 0.110, 0.190, 0.580, 0.590 | 0.110 | 4,249 | 3,833 | 0 | 2 | 1 | 3 | 3 | 2 |
| 4-N | 2 | 0.073, 0.172 | 0.123 | 4,709 | 4,291 | 0 | 0 | 3 | 1 | 1 | 2 |
| 4-J | 1 | 0.126 | 0.126 | 6,508 | 6,026 | 0 | 1 | 6 | 1 | 2 | 2 |
| 2-D | 1 | 0.256 | 0.256 | 9,702 | 8,869 | 0 | 2 | 2 | 1 | 7 | 1 |
| 0-D | 1 | 0.256 | 0.256 | 3,872 | 3,412 | 1 | 3 | 2 | 3 | 5 | 2 |
| 3-Q | 6 | 0.148, 0.198, 0.242, 0.276, 0.291, 0.458 | 0.259 | 5,580 | 5,079 | 2 | 0 | 4 | 2 | 5 | 4 |
| 4-M | 1 | 0.307 | 0.307 | 2,953 | 2,758 | 1 | 0 | 0 | 0 | 2 | 3 |
| 6-6 | 1 | 0.307 | 0.307 | 5,364 | 4,505 | 3 | 0 | 3 | 1 | 4 | 1 |
| 4-E | 2 | 0.340, 0.360 | 0.350 | 3,942 | 3,586 | 0 | 0 | 1 | 0 | 0 | 1 |
| 4-L | 2 | 0.310, 0.485 | 0.398 | 3,069 | 2,723 | 1 | 1 | 1 | 0 | 0 | 1 |
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| No. of | Person-Years | Bladder | Liver | Lung | |||||||
| Village | Wells | Arsenic Concentration, ppm | Median | M | F | M | F | M | F | M | F |
| 4-F | 11 | 0.120, 0.170, 0.229,0.260, 0.260, 0.406,0.469, 0.485, 0.595, 0.779, 0.819 | 0.406 | 4,482 | 3,886 | 2 | 3 | 1 | 0 | 5 | 1 |
| 3-1 | 1 | 0.448 | 0.448 | 4,551 | 4,259 | 2 | 3 | 5 | 1 | 4 | 3 |
| 5-G | 1 | 0.467 | 0.467 | 3,179 | 5,298 | 7 | 5 | 2 | 3 | 7 | 1 |
| 4-P | 1 | 0.504 | 0.504 | 5,843 | 5,397 | 1 | 0 | 1 | 1 | 1 | 1 |
| 0-H | 5 | 0.050, 0.394, 0.520, 0.610,1.752 | 0.520 | 4,390 | 4,313 | 3 | 2 | 4 | 0 | 4 | 5 |
| 4-1 | 47 | 0.020, 0.020, 0.030, 0.090, 0.100, 0.110, 0.120, 0.5200.120, 0.160, 0.190, 0.230, 0.240, 0.250, 0.270, 0.270, 0.290, 0.290, 0.350, 0.370, 0.410, 0.430, 0.450, 0.510, 0.520, 0.540, 0.560, 0.660, 0.700, 0.730, 0.740, 0.760, 0.760, 0.760, 0.780, 0.810, 0.810, 0.840, 0.840, 0.850, 0.850, 0.850, 0.870, 0.880, 0.900, 0.930, 0.940, 0.970 | 0.520 | 4,870 | 4,432 | 2 | 2 | 1 | 0 | 3 | 5 |
| 3-J | 2 | 0.529, 0.529 | 0.529 | 8,454 | 8,689 | 4 | 8 | 3 | 1 | 6 | 5 |
| 3-S | 2 | 0.480, 0.595 | 0.538 | 4,287 | 3,667 | 4 | 3 | 7 | 0 | 8 | 4 |
| 3-9 | 1 | 0.544 | 0.544 | 3,655 | 3,413 | 0 | 1 | 1 | 1 | 1 | 0 |
| 2-2 | 10 | 0.560, 0.580, 0.580, 0.590, 0.597, 0.600, 0.618, 0.620, 0.650, 0.704 | 0.599 | 9,059 | 7,977 | 2 | 2 | 9 | 5 | 8 | 5 |
| 4-G | 2 | 0.620, 0.680 | 0.650 | 2,425 | 2,108 | 2 | 0 | 0 | 0 | 2 | 2 |
| 5-4 | 2 | 0.630, 0.735 | 0.683 | 3,155 | 2,983 | 1 | 1 | 2 | 1 | 5 | 2 |
| 2-M | 2 | 0.435, 0.950 | 0.693 | 11,123 | 11,263 | 9 | 9 | 6 | 4 | 14 | 4 |
| 0-F | 5 | 0.415, 0.660, 0.694, 0.720, 0.749 | 0.694 | 7,010 | 5,720 | 5 | 1 | 8 | 3 | 2 | 9 |
| 3-R | 5 | 0.397, 0.440, 0.698, 0.750,1.010 | 0.698 | 4,310 | 3,576 | 3 | 6 | 3 | 2 | 6 | 7 |
| 3-M | 4 | 0.221, 0.329, 1.105,1.411 | 0.717 | 5,815 | 4,877 | 0 | 1 | 2 | 0 | 0 | 0 |
| 2-N | 3 | 0.560, 0.934, 0.960 | 0.934 | 8,341 | 8,342 | 7 | 10 | 8 | 2 | 4 | 4 |
| aData from Wu et al. 1989; Chen et al. 1992. | |||||||||||
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References
Chen, C.J., C.W. Chen, M.M. Wu, and T.L. Kuo. 1992. Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water. Br. J. Cancer 66:888-892.
Wu, M.M., T.L. Kuo, Y.H. Hwang, and C.J. Chen. 1989. Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases. Am. J. Epidemiol. 130:1123-1232.
