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Action Collaborative

Resilient and Enduring Data Infrastructure for Biomedical and Life Sciences Research and Innovation

The multisector REDI Initiative brings together leaders and experts across academia, industry, government, philanthropy, and nonprofit organizations to advance a future-oriented and resilient biodata ecosystem. As biological and biomedical datasets from genomics and imaging to AI-enabled analytics expand in scale, complexity, and importance, REDI addresses the increasing challenge of keeping these resources effective, accessible, and sustainable over time.

In progress

News and Updates

New Issue Paper on Data Hibernation for Biomedical Data Resources

Update

This Issue Paper discusses data hibernation as one option that can lower the cost of operation for biomedical data resources while enabling future reactivation and reuse. It explores where hibernation fits within the broader context of data resource management; when it may be appropriate; and technical, operational, and governance considerations for its implementation.

Nov 10, 2026

Share Feedback for a New Discussion Paper on Informing Strategic Prioritization of Biodata Resources

Update

A new National Academies discussion draft offers an initial framework for informing strategic prioritization of biodata resources. Researchers, data generators, resource managers, infrastructure providers, funders, policymakers, and others across the biomedical data ecosystem are invited to share feedback to help test and refine the framework and inform subsequent REDI discussions and activities. Does the proposed framework reflect the considerations that matter most when making decisions about biodata resources? Share your input by January 11, 2027.

Nov 10, 2026

Statement of Task

The National Academies of Sciences, Engineering, and Medicine will establish an Initiative for Resilient and Enduring Data Infrastructure for Biomedical and Life Sciences Research and Innovation (REDI Initiative) to foster collaborative action toward sustainable, accessible, and usable data infrastructure. Initiative discussions, workstreams, and activities will:

  • Promote collective action toward sustainable and purpose-driven data infrastructure for biomedical/life sciences research and innovation;
  • Advance attention to and implementation of a lifecycle-based approach to management of biological and biomedical databases from creation to sunsetting;
  • Support the field in experimenting with and learning from new approaches to database sustainability, including business models; and
  • Strengthen multisector, multi-stakeholder collaborative networks.

The Initiative will address the intersection of the use of databases to advance scientific discovery and innovation, the infrastructure and business models required for sustainability, and the move to enhance data access, interoperability, and sharing. It will serve to align and cross-fertilize efforts, avoid duplication, and magnify results among the many experts, organizations, and networks working to address different aspects of funding, sustainability, sharing, curation, and management of biomedical and life sciences databases and associated tools.

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Contributors

Steering Committee

Chair

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Katherine Bowman

Staff Officer

Initiative Membership

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Sponsors

Gates Ventures

National Institutes of Health

Private: Non Profit

Staff

Katherine Bowman

Lead

Trisha Tucholski

John Veras

Maya Frey

Tho Nguyen

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