Toxicologic Risk of Fluoride in Drinking Water

Closed

Fluoride in Drinking Water

June 20 - 21, 2005

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

John Doull, Kim Boekelheide, Barbara Farishian, Robert Isaacson, Jayanth Kumar, Hardy Limeback, Edward Puzas, Ruby Reed, Kathleen Thiessen, Thomas Webster

The following topics were discussed in the closed sessions:

1. Draft report
2. Conclusions and recommendations

The following materials (written documents) were made available to the committee in the closed sessions:

FLU-106: Online Article: Fluoride Action Network. 2005. Fluoride chemicals leach lead into water supplies [Online]. Printout as of May 26, 2005 from the website of Medical News Today.

FLU-107: Online Article: Woffinden, B. 2005. Fluoride water causes cancer?. Boys at risk from bone tumors, shock research reveals [Online]. Printout as of June 14, 2005 from the website of The Observer.

FLU-108: Online Article: Environmental Working Group. 2005. Government asked to evaluate the cancer-causing potential of fluoride in tap water [Online]. Printout as of June 14, 2005 fro the website of the Environmental Working Group.

FLU-109: Letter: Wiles, R. 2005. Letter dated June 6, 2005 from
Richard Wiles, Senior Vice President, Environmental Working Group to C. W.
Jameson, National Toxicology Program.

FLU-110: Submission: Neurath, C. 2005. Correlation between dental
fluorosis incidence and osteosarcoma incidence amongst provinces on Kenya and
association between fluoridation and osteosarcoma in Malaysia.

FLU-111: Article: Chibole, O. 1987. Epidemiology of dental fluorosis
in Kenya. Journal of the Royal Society of Health. 107(6):242-243.

FLU-112: Article: Bovill, Jr., E.G., A. Kung?u, A. Bencivenga, M.K.
Jashran, B.S. Mbindyo, and P.M. Heda. 1985. An epidemiological study of
osteogenic sarcoma in Kenya: the variations in incidence between ethnic groups
and geographic regions, 1968-1978. International Orthopaedics. 9:59-63.

Date of posting of Closed Session Summary:

June 28, 2005

Contact

Tamara Dawson

202-334-2776
tdawson@nas.edu

Location

National Academy of Sciences Building

2101 Constitution Ave NW

Washington DC 20418, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Fluoride in Drinking Water

September 16 - 17, 2004

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

John Doull, Kim Boekelheide, Barbara Farishian, Robert Isaacson, Judith Klotz (17th only), Jayanth Kumar, Hardy Limeback, Edward Puzas, Ruby Reed, Kathleen Thiessen (via conference call), Thomas Webster

The following topics were discussed in the closed sessions:

Draft report
Conclusions and recommendations

The following materials (written documents) were made available to the committee in the closed sessions:

None

Date of posting of Closed Session Summary:

September 20, 2004

Contact

Tamara Dawson

202-334-2776
tdawson@nas.edu

Location

Keck Center

500 5th St NW

Washington DC 20001, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Fluoride in Drinking Water

June 1 - 3, 2004

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

John Doull, Kim Boekelheide, Barbara Farishian, Robert Isaacson, Judith Klotz, Jayanth Kumar, Hardy Limeback, Charles Poole, Edward Puzas, Nu-may Reed, Kathleen Thiessen, Thomas Webster

The following topics were discussed in the closed sessions:

1. Draft report
2. Conclusions and recommendations

The following materials (written documents) were made available to the committee in the closed sessions:

None

Date of posting of Closed Session Summary:

June 15, 2004

Contact

Tamara Dawson

202-334-2776
tdawson@nas.edu

Location

J. Erik Jonsson Woods Hole Center

314 Quissett Avenue

Woods Hole MA 02543, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Fluoride in Drinking Water

February 5 - 6, 2004

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

John Doull, Kim Boekelheide, Barbara Farishian, Robert Isaacson, Judith Klotz, Jayanth Kumar, Hardy Limeback, Charles Poole (by conference call on Feb. 6), Edward Puzas, Nu-may Ruby Reed, Kathleen Thiessen, Thomas Webster

The following topics were discussed in the closed sessions:

1. Draft report
2. Preliminary findings and recommendations

The following materials (written documents) were made available to the committee in the closed sessions:

The chemistry of fluorosilicate hydrolysis in municipal water supplies. A
review of the literature and a summary of the University of Michigan studies.
Prepared by Michael D. Morris, Professor of Chemistry, University of Michigan,
Ann Arbor, MI.

Fluoride Exposure and Osteosarcoma. Chester Douglass, Principal Investigator,
Harvard University. Summary of ongoing study.

Letter from Michael Connett to Susan Martel (National Research Council), dated
January 29, 2004, regarding toxicologic risk of fluoride in drinking water.

Date of posting of Closed Session Summary:

February 11, 2004

Contact

Tamara Dawson

202-334-2776
tdawson@nas.edu

Location

Arnold and Mabel Beckman Center

100 Academy Way

Irvine CA 92617, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Fluoride in Drinking Water

November 10 - 11, 2003

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

John Doull, Kim Boekelheide, Barbara Farishian, Robert Isaacson, Judith Klotz, Jayanth Kumar, Hardy Limeback, Charles Poole, Edward Puzas, Nu-may Ruby Reed, Kathleen Thiessen, Thomas Webster

The following topics were discussed in the closed sessions:

Standard NRC discussion of policies, procedures, conflict of interest, and bias

Report outline and writing assignments

Preliminary review of data

The following materials (written documents) were made available to the committee in the closed sessions:

FLU-58: Public Agenda

FLU-59: Subcommittee Roster

FLU-60: Document
Levy, S.M., J.J. Warren, and B. Broffitt. In press. Patterns of Fluoride
Intake from 36 to 72 Months. J Pub Health Dent.

FLU-61: Document
Marshall, T.A., S.M. Levy, B. Broffitt, J.J. Warren, J.M. Eichenberger-Gilmore,
T.L. Burns, and P.J. Stumbo. 2003. Dental Caries and Beverage Consumption in
Young Children. Pediatrics. 112(3):e184-e191.

FLU-62: Document
Levy, S.M., J.J. Warren, B. Broffitt, S.L. Hillis, and M.J. Kanellis. 2003.
Fluoride, Beverages and Dental Caries in the Primary Dentition. Caries Res.
37:157-165.

FLU-63: Document
Levy, S.M., S.L. Hillis, B.A. Broffitt, A.K.M. Mahbubal Islam, J.S. Wefel, and
M.J. Kanellis. 2002. Primary Tooth Fluorosis and Fluoride Intake During the
First Year of Life. Community Dent Oral Epidemiol. 30:286-295.

FLU-64: Document
Levy, S.M., J.J. Warren, C.S. Davis, L. Kirchner, M.J. Kanellis, and J.S.
Wefel. 2001. Patterns of Fluoride Intake from Birth to 36 Months. J Public
Health Dent. 61(2):70-77.

FLU-65: Document
Whitford, G.M. 1996. The Metabolism and Toxicity of Fluoride. Monographs in
Oral Science, Vol. 16. Basel: Karger. 153 pp.

FLU-66: Document
Rao, H.V., R.P. Beliles, G.M. Whitford, and C.H. Turner. 1995. A
Physiologically Based Pharmacokinetic Model for Fluoride Uptake by Bone. Reg
Toxicol Pharmacol. 22:30-42.

FLU-67: Document
Turner, C.H., M.P. Akhter, and R.P. Heaney. 1992. The Effects of Fluoridated
Water on Bone Strength. J Orthopaedic Res. 10(4):581-587.

FLU-68: Document
Turner, C.H., I. Owan, E.J. Brizendine, W. Zhang, M.E. Wilson, and A.J.
Dunipace. 1996. High Fluoride Intakes Cause Osteomalacia and Diminished Bone
Strength in Rats with Renal Deficiency. Bone. 19(6):595-601.

FLU-69: Document
Turner, C.H., K. Hasegawa, W. Zhang, M. Wilson, Y. Li, and A.J. Dunipace.
1995. Fluoride Reduces Bone Strength in Older Rats. J Dent Res.
74(8):1475-1481.

FLU-70: Slide presentation
Ohanian, E. 2003. USEPA Drinking Water Regulations for Fluoride: A Historic
Perspective. Given by Edward Ohanian, Ph.D., U.S. Environmental Protection
Agency, Office of Water.

FLU-71: Slide presentation
Levy, S. 2003. Fluoride Exposure and Dental Fluorosis in Children. Given by
Steven M. Levy, D.D.S., M.P.H., University of Iowa College of Dentistry,
Department of Preventive and Community Dentistry.

FLU-72: Slide presentation
Whitford, G. 2003. Metabolism and Toxicity of Fluoride. Given by Gary M.
Whitford, D.M.D., Medical College of Georgia, School of Dentistry, Department
of Oral Biology and Maxillofacial Pathology.

FLU-73: Slide presentation
Turner, C. 2003. Effects of Fluoride on Bone. Given by Charles H. Turner,
Ph.D., Indiana University School of Medicine, Department of Orthopaedic
Surgery.

Date of posting of Closed Session Summary:

November 13, 2003

Contact

Tamara Dawson

202-334-2776
tdawson@nas.edu

Location

Keck Center

500 5th St NW

Washington DC 20001, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

Closed

Fluoride in Drinking Water

August 12 - 13, 2003

Past

Additional Information

Is it a Closed Session event?

Institution Closed

The following committee members were present at the closed sessions of the event

Provisional members present:
John Doull, Kim Boekelheide, Barbara Farishian, Robert Isaacson, Judith Klotz, Jayanth Kumar, Charles Poole, Edward Puzas, Nu-May Reed, Kathleen Thiessen, Bernard Wagner, Thomas Webster

The following topics were discussed in the closed sessions:

1. Standard NRC discussion of policies, procedures, conflict of interest and
bias
2. Committee expertise and balance
3. Interpretation of the statement of task, plan of action and report outline
4. Schedule and location of future committee meetings

The following materials (written documents) were made available to the committee in the closed sessions:

FLU-41: Public Agenda

FLU-42: Subcommittee Roster

FLU-43: Document
EPA (U.S. Environmental Protection Agency). 1985. Drinking Water Criteria
Document on Fluoride. U.S. Environmental Protection Agency. Criteria and
Standards Division, Office of Drinking Water. Washington, DC.

FLU-44: Document
EPA (U.S. Environmental Protection Agency). 1986. National Primary and
Secondary Drinking Water Regulations. Code of Federal Regulations, Title 40,
Parts 141, 142 and 143. Fed. Regist. 51(63):11396-11412.

FLU-45: Document
EPA (U.S. Environmental Protection Agency). 1986. National Primary and
Secondary Drinking Water Regulations. Code of Federal Regulations, Title 40,
Part 141. Fed. Regist. 51(93):20164-20175.

FLU-46: Document
CDC (Center for Disease Control and Prevention). 2002. Populations receiving
optimally fluoridated public drinking water?United States, 2000. MMWR,
February 22, 2002. 51(7):144-147.

FLU-47: Document
CDC (Centers for Disease Control). 1991. Public health service report on
fluoride benefits and risks. Centers for Disease Control. JAMA 262:1061-1067.

FLU-48: Document
CDC (Centers for Disease Control and Prevention). 2001. Recommendations for
using fluoride to prevent and control dental caries in the United States.
Morbid. Mortal. Weekly Rep. 50(RR-14):1-42.

FLU-49: Article
Connett, P. 2002. The absurdities of water fluoridation. Available at the
website of www.fluoridealert.org.

FLU-50: Statement
Connett, P. 2000. Fluoride: A statement of concern. Waste Not 459.

FLU-51: Power Point Slide presentation
Connett, P. and M. Connett. 2003. A safe drinking water standard for
fluoride: LOAELS and protecting the most vulnerable. Given by Paul Connett,
Ph.D., St. Lawrence University.

FLU-52: Handout
Connett, P. and M. Connett. 2003. A safe drinking water standard for
fluoride: LOAELS and protecting the most vulnerable. Given by Paul Connett,
Ph.D., St. Lawrence University.

FLU-53: Power Point Slide presentation
Donohue, J. 2003. US EPA drinking water regulations for fluoride. Given by
Joyce Donohue, Ph.D., U.S. Environmental Protection Agency, Office of Water.

FLU-54: Power Point Slide presentation
Maas, W.R. 2003. Fluoride and dental health in the Unites States. Given by
William R. Maas, DDS, MPH, Centers for Disease Control and Prevention, Division
of Oral Health.

FLU-55: Article
Crosby, N.T. 1969. Equilibria of fluorosilicate solutions with special
reference to the fluoridation of public water supplies. J. Appl. Chem.
19:100-102.

FLU-56: Statement
ADA (American Dental Association). Comments to the subcommittee on fluoride in
drinking water of the national research council. August 12, 2003.

Date of posting of Closed Session Summary:

August 20, 2003

Contact

Tamara Dawson

202-334-2776
tdawson@nas.edu

Location

National Academy of Sciences Building

2101 Constitution Ave NW

Washington DC 20418, USA

Disclaimer

It is essential to the National Academies mission of providing evidence-based advice that participants in any of our meetings or events avoid political or partisan statements or commentary and maintain a culture of mutual respect. The statements and presentations during our meetings or events are solely those of the individual participants and do not necessarily represent the views of other participants or the National Academy of Sciences, which is a non-partisan, tax exempt organization that includes under its Charter the National Academy of Engineering and National Academy of Medicine, and that operates the National Research Council.

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Toxicologic Risk of Fluoride in Drinking Water

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Fluoride in Drinking Water

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Fluoride in Drinking Water