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Biomarkers—measurable changes in an organism that serve as indicators of health impairment or disease—have become a cornerstone of medical practice. Recently identified biomarkers that signal conditions such as organ system damage, Alzheimer's disease, and cancer could be used to measure adverse health effects that may arise from exposure to environmental pollutants.
An ad hoc planning committee of the National Academies of Sciences, Engineering, and Medicine will organize and convene a workshop to explore how emerging tools, technologies, and methodologies advance the development of biomarkers of effect, on scales ranging from laboratory-based research to population studies.
Learn more at: https://bit.ly/esehdbiomarkers
Featured publication
Workshop_in_brief
·2020
Biomarkers of effect are measurable changes in an individual that indicate health impairment or disease. Although biomarkers have long been a crucial part of medical practice - blood pressure is a simple example - researchers have recently identified a variety of new biomarkers that signal the prese...
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Description
An ad hoc planning committee of the National Academies of Sciences, Engineering, and Medicine will organize and convene a workshop to explore the state-of-the-art in development of biomarkers of effect -- mining emerging knowledge from model systems and clinical studies to show how new biomarker approaches can be applied to understanding the consequences of environmental exposures and improve environmental health decisions. The workshop will include presentations and panel discussion on topics such as:
- How can “big data” and artificial intelligence approaches be mined to develop early and predictive biomarkers of eventual adverse consequences of environmental exposure?
- What are recent advances in imaging technologies for early detection of nascent disease onset caused by environmental exposures?
- Are there one-size-fits all biomarkers of effect resulting from environmental exposures, or are different biomarkers needed for different individuals to account for human biological diversity, aging, or location?
- What is the sensitivity and specificity of biomarkers of effect?
- What types of evidence are needed to demonstrate and validate the utility of a biomarker of effect for medical and public health decisions?
The presentations and discussions at the workshop will be documented in a workshop proceedings, written by a designated rapporteur in accordance with institutional guidelines.
Contributors
Sponsors
Department of Health and Human Services
Staff
Keegan Sawyer
Lead
Jessica De Mouy
Rebecca Chevat
