On February 25 and 26, 2008, the Forum convened a workshop to discuss screening for colorectal cancer. Colorectal cancer screening rates remain low, despite strong evidence that screening is effective for reducing mortality. This workshop discussed strategies at the clinic, community, and health system level to promote adoption of recommended colorectal cancer screening. Workshop speakers, representing a broad spectrum of leaders in the field, identified major barriers to increased screening and described strategies to overcome these obstacles. This workshop highlighted discussion about actions to increase colorectal screening and, ultimately, to reduce colorectal cancer mortality.