An ad hoc committee will conduct a study that examines current efforts to develop advanced and automated workflows for scientific research. The study will also identify promising research approaches to accelerating progress in the effectiveness and utilization of workflow systems and tools. The committee’s primary information gathering will consist of a workshop that examines the status of research workflows in several example fields, key barriers and enablers, and emerging opportunities. The workshop will explore the role of open science, in the form of broad access to research articles, data, and analytical code, and other enabling factors. Based on insights from the workshop, a review of the literature, and other inputs, the committee will produce a consensus report that identifies research needs and priorities in the use of advanced and automated workflows for scientific research.