Review of Evidence on Alcohol and Health (2025)

Chapter: Appendix D: AMSTAR-2 Tables

Previous Chapter: Appendix C: Timeline of Screening for Eligibility
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

Appendix D

AMSTAR-2 Tables

TABLE D-1 AMSTAR-2 Evaluation for All-Cause Mortality Systematic Reviews with or without Meta-Analyses Published between 2019 and 2024

AMSTAR QuestionStudy (Author, Year)
van de Luitgaarden et al., 2022Zhao et al., 2023Estruch and Hendriks 2022Boushey et al., 2020English et al., 2021Marcos et al., 2021
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyesyesyesyesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?yesyesnoyesyesno
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
van de Luitgaarden et al., 2022Zhao et al., 2023Estruch and Hendriks 2022Boushey et al., 2020English et al., 2021Marcos et al., 2021
Did the review authors explain their selection of the study designs for inclusion in the review?yesyesyesyesyesyes
Did the authors use a comprehensive literature search strategy?yesyesyesyesyesyes
Did the review authors perform study selection in duplicate?yesyesyesyesyesnot known
Did the review authors perform data extraction in duplicate?yesyesyesyesyesnot known
Did the review authors provide a list of excluded studies and justify the exclusions?partialnopartiallyyesn/ano
Did the review authors describe the included studies in adequate detail?yesyesyesyesyesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesn/anoyesyesnot known
Did the review authors report on the sources of funding for the studies included in the review?noyesyesyesyesyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
van de Luitgaarden et al., 2022Zhao et al., 2023Estruch and Hendriks 2022Boushey et al., 2020English et al., 2021Marcos et al., 2021
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?n/ayesn/an/an/an/a
Did the review authors account for RoB in individual studies when interpreting/discussing the results of the review?partialyespartiallyyesyesno
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyesyesyesyesyes
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?n/ayesn/an/an/an/a
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyesyesyesyesyes
OVERALL “QUALITY”moderatemoderatelowhighhighcritically low

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

TABLE D-2 AMSTAR-2 Evaluation for Weight Change Systematic Reviews with or without Meta-Analyses Published Between 2019 and 2024

AMSTAR QuestionStudy (Author, Year)
Golzarand et al., 2022Siegmann et al., 2022
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?yesno
Did the review authors explain their selection of the study designs for inclusion in the review?yesyes
Did the authors use a comprehensive literature search strategy?yesyes
Did the review authors perform study selection in duplicate?yesyes
Did the review authors perform data extraction in duplicate?unknownyes
Did the review authors provide a list of excluded studies and justify the exclusions?noyes
Did the review authors describe the included studies in adequate detail?yesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesyes
Did the review authors report on the sources of funding for the studies included in the review?nono
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?n/ayes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Golzarand et al., 2022Siegmann et al., 2022
Did the review authors account for RoB in individual studies when interpreting/discussing the results of the review?noyes (but did not include RoB score for each study, just that it was accounted for)
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyes
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?yesyes
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyes
OVERALL “QUALITY”lowlow

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

TABLE D-3 AMSTAR-2 Evaluation for Cancer Systematic Reviews with or without Meta-Analyses Published Between 2019 and 2024

AMSTAR QuestionStudy (Author, Year)
Breau and Ellis, 2020Burton et al., 2024Estruch and Hendriks, 2022Fakhri et al., 2022Hua et al., 2023Jun et al., 2023Levesque et al., 2023Luceron-Lucas-Torres et al., 2023McNabb et al., 2020
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyesyesyesyesyesyesyesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?no mention of protocolyesyesno mention of protocolyesyesyesyesno mention of protocol
Did the review authors explain their selection of the study designs for inclusion in the review?yesyesyesyesyesyesyesyesyes
Did the authors use a comprehensive literature search strategy?yesyesyesnoyesyesyesyesn/a
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
Did the review authors perform study selection in duplicate?yesyesyesnot statedyesyesyesyesn/a
Did the review authors perform data extraction in duplicate?yesNoyesnot statedyesyesyesyesn/a
Did the review authors provide a list of excluded studies and justify the exclusions?PartialYespartialnopartialpartialpartialyesn/a
Did the review authors describe the included studies in adequate detail?yesyesyesyesyesyesyesyesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesyesnonoyesyesyesyesnot stated
Did the review authors report on the sources of funding for the studies included in the review?NoNononononononono
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?yesyesn/an/ayesyesn/ayesyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Breau and Ellis, 2020Burton et al., 2024Estruch and Hendriks, 2022Fakhri et al., 2022Hua et al., 2023Jun et al., 2023Levesque et al., 2023Luceron-Lucas-Torres et al., 2023McNabb et al., 2020
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyesyesnoyesyesyesyesyes
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?NoYesn/an/ayesyesn/ayesn/a
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyesyesyesyesyesyesyesyes
OVERALL “QUALITY”critically lowhighlowcritically lowhighmoderatemoderatehighunknown

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Papadimitriou et al., 2021Poorolajal et al., 2021Shin et al., 2023Sun et al., 2023Veettil et al., 2021Wiggs et al., 2021Xu et al., 2019Zhong et al., 2022
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyesyesyesyesyesyesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?no mention of protocolyesyesyesyesno mention of protocolyesyes
Did the review authors explain their selection of the study designs for inclusion in the review?yesyesyesyesyesyesyesyes
Did the authors use a comprehensive literature search strategy?yesyesyesyesyesyesyesyes
Did the review authors perform study selection in duplicate?yesyesyesyesyesyesyesyes
Did the review authors perform data extraction in duplicate?yesyesyesyesyesyesyesyes
Did the review authors provide a list of excluded studies and justify the exclusions?yespartialpartialpartialyespartialpartialyes
Did the review authors describe the included studies in adequate detail?yesyesyesyesyesyesyesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesyesyesyesyesnoyesyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Papadimitriou et al., 2021Poorolajal et al., 2021Shin et al., 2023Sun et al., 2023Veettil et al., 2021Wiggs et al., 2021Xu et al., 2019Zhong et al., 2022
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?n/ayesyesyesn/an/ayesn/a
Did the review authors account for RoB in individual studies when interpreting/discussing the results of the review?yesyesyesyesyespartialyesyes
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyesyesyesyesyesyesyes
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?yesyesyesyesyesn/ayesn/a
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyesyesyesyesyesyesyes
OVERALL “QUALITY”lowmoderatemoderatehighhighcritically lowhighhigh

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

TABLE D-4 AMSTAR-2 Evaluation for Cardiovascular Disease Systematic Reviews with or without Meta-Analyses Published Between 2019 and 2024

AMSTAR QuestionStudy (Author, Year)
Aljuraiban et al., 2024Arafa et al., 2023Del Giorno et al., 2022Giannopoulos et al., 2022Hwang et al., 2021Jung et al., 2020Krittanawong et al., 2022Levesque et al., 2023Liu et al., 2020Marcos et al., 2021
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyesyesyesyesyesyesyesyesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?yesyesyesyesyesnonoyesnono
Did the review authors explain their selection of the study designs for inclusion in the review?yesyesyesyesyesyesyesyesyesyes
Did the authors use a comprehensive literature search strategy?yesyesyesyesyesyesyesyesyesyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Aljuraiban et al., 2024Arafa et al., 2023Del Giorno et al., 2022Giannopoulos et al., 2022Hwang et al., 2021Jung et al., 2020Krittanawong et al., 2022Levesque et al., 2023Liu et al., 2020Marcos et al., 2021
Did the review authors perform study selection in duplicate?yesnot statedyesyesyesyesnot statedyesyesnot stated
Did the review authors perform data extraction in duplicate?yesnot statedyesyesyesyesnot statedyesyesnot stated
Did the review authors provide a list of excluded studies and justify the exclusions?yespartialpartialpartialyesyesnopartialyesno
Did the review authors describe the included studies in adequate detail?yesyesyesyesyesyesyesyesyesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesyesyesyesyesyesnoyesyesno
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
Did the review authors report on the sources of funding for the studies included in the review?yesnonononononononoyes
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?n/ayesn/ayesn/ayesn/an/ayesn/a
Did the review authors account for RoB in individual studies when interpreting/discussing the results of the review?yesyesnoyesyesyesnoyesyesno
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyesyesyesyesyesyesyesyesyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Aljuraiban et al., 2024Arafa et al., 2023Del Giorno et al., 2022Giannopoulos et al., 2022Hwang et al., 2021Jung et al., 2020Krittanawong et al., 2022Levesque et al., 2023Liu et al., 2020Marcos et al., 2021
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?n/ayesn/ayesn/ayesn/an/ayesn/a
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyesyesyesyesyesyesyesyesyes
OVERALL “QUALITY”highmoderate lowmoderatehighlowcritically lowmoderatelowcritically low

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Siagian et al., 2023Spaggiari et al., 2020Tasnim et al., 2020van de Luitgaarden et al., 2022Wilkens et al., 2022Yang et al., 2022Yoon et al., 2020Zhang et al., 2021Zhong et al., 2022
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyesyesyesyesyesyesyesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?yesyesyesyesyesnononoyes
Did the review authors explain their selection of the study designs for inclusion in the review?yesyesyesyesyesyesyesyesyes
Did the authors use a comprehensive literature search strategy?yesyesyesyesyesyesyesyesyes
Did the review authors perform study selection in duplicate?yesyesyesyesyesyesyesyesyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Siagian et al., 2023Spaggiari et al., 2020Tasnim et al., 2020van de Luitgaarden et al., 2022Wilkens et al., 2022Yang et al., 2022Yoon et al., 2020Zhang et al., 2021Zhong et al., 2022
Did the review authors perform data extraction in duplicate?yesyesyesyesyesyesyesyesyes
Did the review authors provide a list of excluded studies and justify the exclusions?partialyesyespartialpartialpartialpartialpartialyes
Did the review authors describe the included studies in adequate detail?yesyesyesyesyesyesyesyesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesyesyesyesyesyesyesyesyes
Did the review authors report on the sources of funding for the studies included in the review?nonoyesnononononono
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?yesyesyesn/an/ayesyesyesn/a
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
Did the review authors account for RoB in individual studies when interpreting/discussing the results of the review?noyesyesyesyesyesyesnoyes
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyesyesyesyesyesyesyesyes
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?noyesyesn/an/ayesyesyesyes
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyesyesyesyesyesyesyesyes
OVERALL “QUALITY”critically lowhighhighmoderatemoderatelowlowcritically lowhigh

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

TABLE D-5 AMSTAR-2 Evaluation for Neurocognitive Health Systematic Reviews with or without Meta-Analyses Published Between 2019 and 2024

AMSTAR QuestionStudy (Author, Year)
Brennan et al., 2020Jones et al., 2024Kilian et al., 2023Lao et al., 2021Luceron-Lucas-Torres et al., 2022Porras-Garcia et al., 2023Ran et al., 2021Visontay et al., 2022Wiegmann et al., 2020Xie and Feng, 2022
Did the research questions and inclusion criteria for the review include ALL the components of PICO?yesyesyesyesyesyesyesyesyesyes
Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?yesyesyesyesyesyesyesyesNopartial
Did the review authors explain their selection of the study designs for inclusion in the review?yesyesyesyesyesyesyesyesyesyes
Did the authors use a comprehensive literature search strategy?yesyesyesyesyesyesyesyesyesyes
Did the review authors perform study selection in duplicate?yesyesyesyesyesyesyesyesnot determinedyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
Did the review authors perform data extraction in duplicate?yesyesyesyesyesyesyesyesnot determinedyes
Did the review authors provide a list of excluded studies and justify the exclusions?yesyesyesyesyesyesyesyesnoyes
Did the review authors describe the included studies in adequate detail?yesyesyesyesyesyesyesyesyesyes
Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?yesyesyesyesyesyesyesyesnot performedyes
Did the review authors report on the sources of funding for the studies included in the review?yesnonononononononono
If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?n/an/an/ayesyesn/ayesn/an/ayes
Did the review authors account for RoB in individual studies when interpreting/discussing the results of the review?yesnoyesyesyesyesyesyesNoyes
Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.
AMSTAR QuestionStudy (Author, Year)
Brennan et al., 2020Jones et al., 2024Kilian et al., 2023Lao et al., 2021Luceron-Lucas-Torres et al., 2022Porras-Garcia et al., 2023Ran et al., 2021Visontay et al., 2022Wiegmann et al., 2020Xie and Feng, 2022
Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?yesyesyesyesyesyesyesyesyesyes
If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?yesn/an/aYesyesn/ayesn/an/ayes
Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?yesyesyesyesyesyesyesyesyesyes
OVERALL “QUALITY”highlowhighhighhighhighhighhighcritically lowhigh

NOTES: n/a = not applicable; PICO = population, intervention, comparator, outcome; RoB = risk of bias.

Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

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Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

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Suggested Citation: "Appendix D: AMSTAR-2 Tables." National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. doi: 10.17226/28582.

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