The National Academies Forum on Advancing Diagnostic Excellence will host a hybrid public workshop to explore the opportunities and challenges for improving diagnosis in the era of digital health and artificial intelligence. Workshop participants will consider policy strategies and research opportunities to improve timely and accurate diagnosis in the context of these diagnostic innovations. Topics of discussion will include: development and validation of diagnostic algorithms; strategies for broad, equitable implementation of effective diagnostic innovations; disparities in access to new technologies and strategies to reduce these barriers; and ways to ensure data security, protect patient privacy, and avoid unintended consequences.