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Improving Drug Development for Dry Age-related Macular Degeneration (AMD): A Workshop

Completed

Topics

There is strong interest across many stakeholders to increase progress around developing treatments for dry age-related macular degeneration (AMD). Advancements in drug discovery and development in dry AMD have been limited and slow due to issues surrounding disease characterization, surrogate endpoints, and clinical trial design. Given the pressing need for progress in the field, the Forum on Neuroscience and Nervous System Disorders hosted a public workshop on November 15, 2014, bringing together key stakeholders, to discuss opportunities for advancing drug development for dry AMD, specifically geographic atrophy.

About Past Events

Description

An ad hoc committee will plan and host a one-day public workshop that will explore the science necessary to overcome current challenges associated with drug discovery and development to support dry age-related macular degeneration (AMD). Specifically, presentations and discussions will be designed to help participants:

  • Consider scientific opportunities and challenges in identifying and validating potential new targets for intervention;
  • Discuss opportunities to improve current and develop new animal models for dry AMD; and
  • Consider the evidence needed to use potential biomarkers as surrogate end points in clinical trials, and how to generate that evidence.

The committee will develop the agenda for the workshop session, select and invite speakers and discussants, and moderate the discussions. An individually authored brief workshop summary based on the presentations and discussions held during the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Collaborators

Committee

Matthew McMahon

Co-Chair

David Michelson

Co-Chair

Anthony Adamis

Member

Daniel J. Burch

Member

Wen Chen

Member

Judith Delgado

Member

David Eveleth

Member

Cynthia Owsley

Member

Stephen M. Rose

Member

Philip J. Rosenfeld

Member

Rhett Schiffman

Member

Michael R. Schwartz

Member

Janet Sunness

Member

Download all bios

Sponsors

Department of Health and Human Services

National Science Foundation

Other, Federal

Private: For Profit

Private: Non Profit

Staff

Diana Pankevich

Lead

Clare Stroud

Lead

Sheena Posey Norris

Major units and sub-units

Institute of Medicine

Lead

Board on Health Sciences Policy

Lead

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