Issues in Risk Assessment (1993)
Chapter: Appendix D Workshop Program
Appendix D
Workshop Program
Thursday, September 6, 1990
Lecture Room, National Academy of Sciences
2101 Constitution Ave., NW
Washington, DC
9:00 | Introduction and Objectives: Kenny Crump, Clement Associates; Chairman |
9:15 | Definition and Application of MTD |
| Presenter: Eugene McConnell, Raleigh, NC |
9:45 | Discussants: John Emmerson, Eli Lilly and Co.; Ian Munro, University of Guelph |
10:05 | Questions and Comments |
10:15 | Break |
10:30 | Correlations between the MTD and Measures of Carcinogenic Potency: Implications for Risk Assessment |
| Presenter: Daniel Krewski, Health and Welfare Canada |
11:15 | Discussants: Kenny Crump, Clement Associates; Lauren Zeise, California Department of Health Services; Thomas Starr, Environ Corp.; |
| Edmund Crouch, Cambridge Environmental, Inc. |
12:00 | Questions and Comments |
12:30 | Lunch |
2:00 | What are Bioassays Conducted at the MTD Telling Us? |
| Presenter: Bruce Ames, University of California, Berkeley |
2:45 | Discussants: Michael Gallo, University of Medicine and Dentistry of New Jersey; David Gaylor, National Center for Toxicological Research |
3:15 | Questions and Comments |
3:30 | Break |
3:45 | General Discussion |
| Leader: Kenny Crump, Clement Associates |
| Issues: |
| • The basis of the observed correlation between the MTD and measures of carcinogenic potency • The possible influence on biological processes of dosing at this level • The implications for the design of rodent bioassays • The implications for carcinogenic risk assessment |
5:00 | Adjourn |
