| APHIS | Animal and Plant Health Inspection Service |
| Cas9 | CRISPR associated protein 9 |
| CERCLA | Comprehensive Environmental Response, Compensation, and Liability Act |
| CRISPR | Clustered regularly-interspaced short palindromic repeats |
| DNA | deoxyribonucleic acid |
| EA | environmental assessment |
| EIS | environmental impact statement |
| EPA | US Environmental Protection Agency |
| FDA | US Food and Drug Administration |
| FIFRA | Federal Insecticide, Fungicide, and Rodenticide Act |
| GMM | genetically modified mosquito |
| GMO | genetically modified organism |
| gRNA | guide ribonucleic acid |
| HDR | homology directed repair |
| HEG | homing endonuclease gene |
| HGT | horizontal gene transfer |
| IACUC | Institutional Animal Care and Use Committee |
| IBC | Institutional Biosafety Committee |
| LMO | living modified organism |
| Medea | Maternal-effect dominant embryonic arrest |
| NEPA | National Environmental Policy Act |
| NGS | next generation sequencing |
| NHEJ | non-homologous end joining |
| NIH | National Institutes of Health |
| NRC | National Research Council |
| NSABB | National Science Advisory Board for Biodefense |
| OSTP | Office of Science and Technology Policy |
| PAM | protospacer adjacent motif |
| RAC | Recombinant DNA Advisory Committee |
| RCRA | Resource Conservation and Recovery Act |
| rDNA | recombinant DNA |
| RIDL | release of insects with dominant lethality |
| RNAi | RNA interference |
| RRM | relative risk model |
| SD | Segregation Distorter |
| SIT | sterile insect technique |
| SOP | standard operating procedure |
| TALEN | Transcription activator-like effector nuclease |
| TPP | target product profile |
| TSCA | Toxic Substances Control Act |
| USDA | US Department of Agriculture |
| USFWS | US Fish and Wildlife Service |
| WHO | World Health Organization |
| ZFN | zinc finger nuclease |